Syntheses of 7-Alkyl-1,3,6-trimethylpyrrolo[2,3-d]pyrimidines and 4-Alkylamino-2,5-dimethyl-2,3-dihydrofuro[3,2-e]pyrimidines

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概要

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• 7-Alkyl-1,3,6-trimethylpyrrolo[2,3-d]pyrimidine-2,4(1H, 3H)-diones were readily synthesized by treatment of 6-alkylamino-5-allyl-1,3-dimethyluracils, which were derived from 5-allyl-6-chloro-1,3-dimethyluracil and alkylamines, with bis(acetonitrile) palladium (II) chloride. In addition, 4-alkylamino-2,5-dimethyl-2,3-dihydrofuro[3,2-e]pyrimidin-6-ones were easily synthesized by treatment of 5-allyl-6-chloro-1-methyluracil with alkylamines.

• 社団法人日本薬学会の論文
• 1992-04-25

著者

• 水野 義久

  School Of Pharmaceutical Sciences Kitasato University

• 水野 義久

  北海道大学 薬

• 小倉 治夫

  School of Pharmaceutical Sciences, Kitasato University

• 小倉 治夫

  School Of Pharmaceutical Sciences Kitasato University

• 石川 一郎

  School of Pahrmaceutical Sciences, Kitasato University

• 川原 徳夫

  Hokkaido Institute of Pharmaceutical Sciences

• 川原 徳夫

  北海道薬大

• 石川 一郎

  School Of Pharmaceutical Sciences Kitasato University

• KHACHATRIAN Victor

  School of Pharmaceutical Sciences, Kitasato University

• MELIK-OHANJANIAN Raphael

  the Department of Heterocyclic Chemistry, Mnjoyan Institute of Fine Organic Chemistry, Academy of Sc

• Melik-ohanjanian Raphael

  The Department Of Heterocyclic Chemistry Mnjoyan Institute Of Fine Organic Chemistry Academy Of Scie

• Khachatrian Victor

  School Of Pharmaceutical Sciences Kitasato University

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