Derivatives of Imidazo [2,1-b] benzoxazole (Studies on Heterocyclic Compounds. VIII)
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概要
- 論文の詳細を見る
Imidazo [2,1-b] benzoxazoles which have a new ring system were synthesized. Condensation reaction of 2-aminobenzoxazole (I) and bromoacetone afforded 2-imino-3-(2-oxopropyl)-2,3-dihydrobenzoxazole (IIa). When phenacyl bromide was used instead of bromoacetone, 2-imino-3-phenacyl-2,3-dihydrobenzoxazole (IVa) was obtained. Cyclization of these imino-derivatives afforded imidazo [2,1-b] benzoxazoles. On the other hand, imidazo [2,1-b] benzoxazole (XIII) was prepared from 1-(o-chlorophenyl)-2-hydroxyimidazole (XI) via benzyne intermediate.
- 社団法人日本薬学会の論文
- 1970-11-25
著者
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小倉 治夫
School of Pharmaceutical Sciences, Kitasato University
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小倉 治夫
School Of Pharmaceutical Sciences Kitasato University
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伊東 常男
School of Pahrmaceutical Sciences, Kitasato University
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伊東 常男
School Of Pharmaceutical Sciences Kitasato University
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杉本 信吾
School of Pharmaceutical Sciences, Kitasato University
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杉本 信吾
北里大学薬学部
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