Studies on Heterocyclic Compounds. XVII. Reaction of 6-Mercapto-1,3-Dimethyluracil with Electrophilic Reagents
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概要
- 論文の詳細を見る
Attempts to prepare 5-oxothiopyrano [2,3-d] pyrimidine derivatives by the reaction of 6-mercapto-1,3-dimethyluracil (I) with various acetylenecarboxylates and ethyl ethoxymethylenecyanomalonate have led instead to the synthesis of substituted thiopyrimidine-2,4-dione. the condensation of (I) with diethyl ethoxymethylenemalonate yielded readily the corresponding 5-oxothiopyrano [2,3-d] pyrimidine-2,4-dione. Elimination of ethoxycarbonyl group in V obtained 1,3-dimethyl-5-oxothiopyrano [2,3-d] pyrimidine-2,4-dione.
- 社団法人日本薬学会の論文
- 1976-06-25
著者
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小倉 治夫
School of Pharmaceutical Sciences, Kitasato University
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小倉 治夫
School Of Pharmaceutical Sciences Kitasato University
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伊東 常男
School of Pahrmaceutical Sciences, Kitasato University
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伊東 常男
School Of Pharmaceutical Sciences Kitasato University
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本間 三重子
School of Pharmaceutical Sciences, Kitasato University
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本間 三重子
School Of Pharmaceutical Sciences Kitasato University
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