Dioxopyrrolines. XXXVI. [2+2] photocycloaddition Reaction of 4-Ethoxycarbonyl-5-phenyl-1H-pyrrole-2,3-dione to Acyclic Olefins. Structural and Stereochemical Assignment of the Photocycloadducts(Organic,Chemical)

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概要

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• The photocycloaddition of the dioxopyrroline 1 to olefins with electron donating substituents proceeded with regio- and stereo-selectivity to give the 7-substituted 2-azabicyclo[3.2.0]heptane-3,4-diones 2 and 3, together with, in a few instances, the dihydropyridone 4. The stereochemistries of the[2+2] adducts were dependent on the nature of the olefins. Olefins carrying phenyl, vinyl, and alkyl substituents afforded the exo-adducts 2, while olefins carrying an O-substituent affordcd the endo-adducts 3, predominantly. The structures of these cycloadducts were established by X-ray crystallographic analyses, chemical correlations, and spectroscopic means.

• 公益社団法人日本薬学会の論文
• 1987-01-25

著者

• 津田 喜典

  Faculty of Pharmaceutical Sciences, Kanazawa University

• 古畑 公夫

  School of Pharmaceutical Sciences, Kitasato University

• 小倉 治夫

  School of Pharmaceutical Sciences, Kitasato University

• 高柳 弘明

  School of Pharmaceutical Sciences, Kitasato University

• 小倉 治夫

  School Of Pharmaceutical Sciences Kitasato University

• 津田 喜典

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 佐野 武弘

  Showa College of Pharmaceutical Sciences.

• 堀口 よし江

  昭和薬大

• 高柳 弘明

  北里大学薬学部薬化学教室

• 高柳 弘明

  School Of Pharmaceutical Sciences Kitasato University

• 津田 喜典

  金沢大薬

• 堀口 よし江

  Showa College of Pharmaceutical Sciences

• 佐野 武弘

  Showa Pharmaceutical Univ. Tokyo Jpn

• 佐野 武弘

  Showa College Of Pharmaceutical Sciences

• 堀口 よし江

  Showa College Of Pharmaceutical Sciences University Of Kanazawa

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