Dioxopyrrolines. XXXV. Synthesis of 2H-Azepin-2-ones (2-Azatropones)

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概要

• 論文の詳細を見る

• Eliminative ring expansion of 4-acetoxy (or mesyloxy)-2-azabicyclo [3.2.0] heptan-3-ones (7) yielded 1,5-dihydro-2H-azepin-2-ones (dihydro-2-azatropones) which, on DDQ oxidation, afforded the 2H-azepin-2-ones (2-azatropones, 9). In contrast to azatropolones, the 2-azatropones were stable to protic solvents. However, irreversible solvolytic changes were observed in both acidic and basic media.

• 公益社団法人日本薬学会の論文
• 1985-12-25

著者

• 津田 喜典

  Faculty of Pharmaceutical Sciences, Kanazawa University

• 津田 喜典

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 佐野 武弘

  Showa College of Pharmaceutical Sciences.

• 堀口 よし江

  昭和薬大

• 津田 喜典

  金沢大薬

• 堀口 よし江

  Showa College of Pharmaceutical Sciences

• 田中 和彦

  Showa College Of Pharmaceutical Sciences

• 佐野 武弘

  Showa Pharmaceutical Univ. Tokyo Jpn

• 佐野 武弘

  Showa College Of Pharmaceutical Sciences

• 堀口 よし江

  Showa College Of Pharmaceutical Sciences University Of Kanazawa

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