Synthesis and Reactions of 3,7-Cycloerythrinan : Skeletal Rearrangement of 2,7,8-Trioxoerythrinans to 4-Oxo-4H-pyrido[2,1,-a]isoquinolines

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概要

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• Treatment of 2,7,8-trioxoerythrinan derivatives with anhydrous phosphoric acid or Lewis acids gave 3,7-cycloerythrinan derivaties via an intramolclar aldol condensation. The structures of the products were established by spectroscopic and chemical means. Further treatment of the 3,7-cycloerythrinans with anhydrous phosphoric acid resulted in skeletal rearrangement to yield 6,7-dihydro-4-oxo-4H-pyrido[2,1-a]isoquinolines, whose structures were also determined mainly by spectroscopic means.

• 社団法人日本薬学会の論文
• 1991-06-25

著者

• 津田 喜典

  Faculty of Pharmaceutical Sciences, Kanazawa University

• 酒井 由紀

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 津田 喜典

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 佐野 武弘

  Showa College of Pharmaceutical Sciences.

• 津田 喜典

  金沢大薬

• 戸田 潤

  Showa College of Pharmaceutical Sciences

• 佐野 武弘

  昭和薬科大学

• 佐野 武弘

  Showa Pharmaceutical Univ. Tokyo Jpn

• 佐野 武弘

  Showa College Of Pharmaceutical Sciences

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