Stereoselective Transformation of the Alkaloid Lycorine to O-Demethylungiminorine and Ungiminorine

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概要

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• Diacetyllycorine, an Amaryllidaceae alkaloid, was transformed stereoselectively to the more heavily oxygenated congener, O-demethylungiminorine, by a route similar to that suggested for the biosynthesis of narcissidine. Similarly, acetylhippamine was converted to ungiminorine. A method of high yield conversion of lycorine to hippamine is also described. The above transformations constitute a formal total synthesis of ungiminorine.

• 公益社団法人日本薬学会の論文
• 1982-04-25

著者

• 津田 喜典

  Faculty of Pharmaceutical Sciences, Kanazawa University

• 板谷 芳京

  Faculty of Pharmaceutical Sciences, Kanazawa University

• 津田 喜典

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 佐野 武弘

  Showa College of Pharmaceutical Sciences.

• 津田 喜典

  金沢大薬

• 戸田 潤

  Showa College of Pharmaceutical Sciences

• 板谷 芳京

  金沢大学薬学部

• 佐野 武弘

  Showa College Of Pharmaceutical Sciences

• 板谷 芳京

  Faculty Of Pharmaceutical Sciences Kanazawa University

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