Studies toward Total Synthesis of Non-aromatic Erythrina Alkaloids.(3). Synthesis of β-Erythroidine Skeleton (β-Erythroidan)

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概要

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• The β-erythroidine skeleton (β-erythroidan) was synthesized as the 8-oxo derivative by two different routes. One is a four-step synthesis starting from 15,16,17-trimethoxy-8-oxo-cis-erythrinan (2) via ozonolytic cleavage of the aromatic ring. The other is a five-step synthesis starting from D-furano-8-oxo-cis-erythrinan (13) via oxidative cleavage of the furan ring. The two routes gave the same 14,17-dihydro-16(15H)-oxaerythrinan-8,15-dione (1) (8-oxo-β-erythroidan). 8-Oxo-β-erythroidan (1) was not identical with the compound previously reported by Kitahara and Matsui, suggesting that their synthesis is questionable.

• 社団法人日本薬学会の論文
• 1992-10-25

著者

• 津田 喜典

  Faculty of Pharmaceutical Sciences, Kanazawa University

• 毛利 邦彦

  Showa College Of Pharmaceutical Sciences

• 礒部 公明

  Showa College of Pharmaceutical Sciences

• 武田 尚子

  Showa College of Pharmaceutical Sciences

• 細井 深造

  Faculty of Pharmaceutical Sciences, Kanazawa University

• 伊藤 裕至

  Showa College of Pharmaceutical Sciences

• 豊川 夕姫

  Showa College of Pharmaceutical Sciences

• 夛賀 淳一

  Showa College of Pharmaceutical Sciences

• 細井 深造

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 津田 喜典

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 津田 喜典

  金沢大薬

• Mohri K

  Showa College Of Pharmaceutical Sciences

• Isobe K

  Showa College Of Pharmaceutical Sciences

• 多賀 淳一

  Showa College Of Pharmaceutical Sciences:kanazawa University

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