Synthesis of Highly Deydrogenated Oxoerythrinan Alkaloids, Erytharbine and Crystamidine

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概要

• 論文の詳細を見る

• 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) oxidation of 3,8-dioxyoerythrinan-1(6)-enes in dioxane gave the ring B dehydrogenated products, the 1,6-dienones, while oxidation in benzene gave the fully dehydrogenated products, the 1,6,10-trienones. The same trienones were obtained by DDQ oxidation of the 1,6-dienones in bezene. On the contrary, oxidation of the isomeric enone, 3,8-dioxoerythrinan-1-ene, in either dioxane or benzene gave the ring C dehydrogenated product, the 1,10-dienone. The 1,6,10-trienones were transformed to the highly dehydrogenated 8-oxoerythrinan alkaloids, erytharbine and crystamidine, in racemic forms.

• 社団法人日本薬学会の論文
• 1993-05-15

著者

• 津田 喜典

  金沢大学

• 津田 喜典

  Faculty of Pharmaceutical Sciences, Kanazawa University

• 細井 信造

  Faculty of Pharmaceutical Sciences, Kanazawa University

• 細井 深造

  Faculty of Pharmaceutical Sciences, Kanazawa University

• 細井 深造

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 細井 信造

  金沢大薬

• 津田 喜典

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 佐野 武弘

  Showa College of Pharmaceutical Sciences.

• 山本 隆三

  Showa College Of Pharmaceutical Sciences

• Kiuchi Fumiyuki

  Faculty of Pharmacy, Keio University

• 津田 喜典

  金沢大薬

• 戸田 潤

  Showa College of Pharmaceutical Sciences

• 佐野 武弘

  昭和薬科大学

• 佐野 武弘

  Showa Pharmaceutical Univ. Tokyo Jpn

• 佐野 武弘

  Showa College Of Pharmaceutical Sciences

• Kiuchi F

  Graduate School Of Pharmaceutical Sciences Kyoto University

• Kikuchi F

  Faculty Of Pharmaceutical Sciences Kanazawa University:(present Address)graduate School Of Pharmaceu

• Kiuchi Fumiyuki

  Faculty Of Pharmaceutical Sciences Kanazawa University

• Kiuchi F

  Kanazawa Univ. Kanazawa Jpn

• 木内 文之

  慶應義塾大学薬学部

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