Studies on Nucleoside Analogs. XXI. : A Convenient Synthesis of 1,2,4-Triazole-5-thione Glycosides
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概要
- 論文の詳細を見る
The reaction of glycosyl isothiocyanates (1a-c) with acyl or aroyl hydrazine, followed by treatment with Ac_2O-H_3PO_4,afforded 1,2,4-triazole-5-thione glycosides (20a, 21a-c, 22a) in fair yields. Attempts to prepare 1,2,4-triazole glycoside analogs with acetic anhydride or sodium methoxide failed. The reaction of glycosyl-2-(phenyl-or pyrid-2-ylhydrazine) thiocarboxamides (6a, 7a) with phosgene in pyridine or triethylamine gave thiadiazole-5-thiones (8a, 9a) instead of 1,2,4-triazole glycosides.
- 社団法人日本薬学会の論文
- 1981-08-25
著者
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小倉 治夫
School of Pharmaceutical Sciences, Kitasato University
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高橋 洋
School Of Pharmaceutical Sciences Kitasato University
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小倉 治夫
School Of Pharmaceutical Sciences Kitasato University
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佐藤 収
School of Pharmaceutical Sciences, Kitasato University
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佐藤 収
School Of Pharmaceutical Sciences Kitasato University
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