Heterocycles. XXII. : Stereoselective Synthesis of (+)-Aromadendrin Trimethyl Ether and Its Enantiomer, and Their Reduction
スポンサーリンク
概要
- 論文の詳細を見る
Two enantiomeric chalcone epoxides 2a and 2b are synthesized under phase-transfer conditions using 1-benzylquinidinium chloride and 1-benzylquininium chloride as catalysts, respectively Stereoselective cyclization of 2a and 2b, followed by methylation and preparative high performance liquid chromatography gives pure (+)-aromadendrin trimethyl ether (4a) and its enantiomer 4b. Reduction of pure 4a and 4b with NaBH_4. affords four pure flavan-3,4-diol trimethyl ethers, 5a, 6a, 5b, and 6b.
- 社団法人日本薬学会の論文
- 1988-05-25
著者
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恩田 政行
School of Pharmaceutical Sciences, Kitasato University
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高橋 洋
School Of Pharmaceutical Sciences Kitasato University
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恩田 政行
Shenyang Pharmaceutical University
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針谷 義弘
北里大薬
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針谷 義弘
School of Pharmaceutical Sciences, Kitasato University
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李 紹順
School of Pharmaceutical Sciences, Kitasato University
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李 紹順
Shenyang Pharmaceutical University
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