37 新規抗菌抗生物質Aurantininの生合成的手段による構造決定(口頭発表の部)

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概要

• 論文の詳細を見る

• A novel antibiotic, aurantinin has been isolated from the cultured broth of Bacillus aurantinus. The antibiotic shows a potent antimicrobial activity against Gram-positive bacteria, especially anaerobes. The structures of aurantinins A and B were assigned by biosynthetic means using feeding experiments of ^<13>C labeled precursors including 2D-NMR and LSPD studies. Aurantinins are a novel skeleton containing four rings, a triene and an acid unhydride moiety. The antibiotic also possesses an unusual polyketide skeleton which we never find out such a biosynthetic building unit in a secondary metabolite from actinomycetes and fungi.

• 天然有機化合物討論会の論文
• 1987-07-25

著者

• 中川 彰

  帝京大理工

• 大村 智

  北里研究所生物機能研究所

• 大村 智

  北里大薬:北里研

• 恩田 政行

  Shenyang Pharmaceutical University

• 中川 彰

  北里大・薬

• 根田 八重子

  北里大・薬

• 波田野 朗子

  北里大・薬

• 恩田 政行

  北里大・薬

• 大村 智

  北里大・薬

• 波田 野朗子

  北里大・薬:北里研

• 波田野 朗子

  School Of Pharmaceutical Sciences Kitasato University

• 根田 八重子

  北里大・薬:北里研

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