Formation of 4-p-Bromophenyl-5-hydroxy-3-methoxycarbonyl-5,6-dihydro-4H-1,2-oxazine by Means of New Ring Transformation of an Isoxazoline-2-oxide

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概要

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• 4-p-Bromophenyl-5-hydroxymethyl-3-methoxycarbonyl-2-isoxazoline-2-oxide methanesulfonate (1c) reacted with excess titanium tetrabromide in dichloromethane to yield a novel ring transformation product, 4-p-bromophenyl-5-hydroxy-3-methoxycarbonyl-5,6-dihydro-4H-1,2-oxazine (2). The structural determination of 2 by single-crystal X-ray analysis is reported.

• 社団法人日本薬学会の論文
• 1992-07-25

著者

• 小倉 治夫

  School of Pharmaceutical Sciences, Kitasato University

• 高柳 弘明

  School of Pharmaceutical Sciences, Kitasato University

• 高柳 弘明

  北里大・薬

• 小倉 治夫

  北里大学

• 小倉 治夫

  School Of Pharmaceutical Sciences Kitasato University

• 高柳 弘明

  北里大学薬学部薬化学教室

• 高柳 弘明

  School Of Pharmaceutical Sciences Kitasato University

• 原田 和穂

  School of Pharmaceutical Sciences, Kitasato University

• 膳 昭之助

  School of Pharmaceutical Sciences, Kitasato University

• 梶 英輔

  School Of Pharmaceutical Sciences Kitasato University

• 膳 昭之助

  北里大学薬学部

• 原田 和穂

  北里大学薬学部

• 下園 優子

  School of Pharmaceutical Sciences, Kitasato University

• 下園 優子

  北里大学薬学部

• 膳 昭之助

  北里大薬

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