Studies on Metal Complexes of Isocytosine Derivative : The Crystal Structure of Zinc (II) Complex of 2-Hydrazino-4-hydroxy-6-methylpyrimidine

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概要

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• The crystal structure of Zn (II) complex of 2-hydrazino-4-hydroxy-6-methylpyrimidine (LH), has been determined from three-dimensional X-ray diffractometer data by heavy atom Fourier methods. Crystals of [Zn(C_5H_8N_4O)_2 (H_2O)_2] Cl_2・2H_2O are triclinic with unit cell dimensions a=8.912 (3), b=9.298 (2), c=6.821 (5) A, α=93.11 (5)°, β=102.14 (4)°, γ=114.33 (2)°, space group P^^1,and Z=1. Block-diagonal least-squares refinement using 1537 independent reflexions yielded the R value of 0.050. The zinc (II) ion completes an octahedral coordination with two ring nitrogen and two amino nitrogen atoms of the two neighbouring ligand molecules and two water molecules. The chloride ions are not bonded to zinc (II) ion but to N (1)-H of the pyrimidine base.

• 公益社団法人日本薬学会の論文
• 1977-09-25

著者

• 飯高 洋一

  Faculty of Pharmaceutical Sciences, The University of Tokyo

• 小倉 治夫

  School of Pharmaceutical Sciences, Kitasato University

• 小倉 治夫

  School Of Pharmaceutical Sciences Kitasato University

• 飯高 洋一

  School Of Medicine Teikyo University

• 飯高 洋一

  西東京科学大学理工学部

• 坂口 洋

  School of Hygienic Sciences, Kitasato University

• 坂口 洋

  School Of Hygienic Sciences Kitasato University

• 安斎 博

  School of Hygienic Sciences, Kitasato University

• 安斎 博

  School Of Hygienic Sciences Kitasato University

• 飯高 洋一

  Faculty Of Pharmaceutical Sciences The University Of Tokyo

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