Potential Antimetabolites. VI. An Improved Synthesis of 2-β-D-Ribofuranosyl-as-triazine-3,5 (2H, 4H)-dione (6-Azauridine).
スポンサーリンク
概要
- 論文の詳細を見る
Our previous method of prepraring azapyrimidine nucleosides is suitable for the preparation of 2-β-D-ribofuranosyl-5-amino-as-triazine-3 (2H)-one (6-azacytidine) (V). For the preparation of 2-β-D-ribofuranosyl-as-triazine-3,5 (2H, 4H)-dione (6-azauridine) (VI), however, an alternative route by way of 2-(2', 3', 5'-tri-O-benzoyl-β-D-ribofuranosyl)-5-methylmercapto-as-triazine-3 (2H)-one (III) was found to be more convenient than the previous one. The procedure was also improved.
- 公益社団法人日本薬学会の論文
- 1963-03-25
著者
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水野 義久
School Of Pharmaceutical Sciences Kitasato University
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水野 義久
Faculty Of Pharmacy Kanazawa University
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水野 義久
北海道大学 薬
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池原 森男
Faculty of Pharmaceutical Sciences, Osaka University(Present address)
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渡辺 恭一
Sloan-kettering Instiute For Cancer Research Memorial Sloan-kettering Cancer Center:sloan-kettering
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渡辺 恭一
Faculty of Pharmaceutical Sciences Hokkaido University, School of Medicine
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池原 森男
Faculty Of Pharmaceutical Sciences Osaka University
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