Studies on Transfer Ribonucleic Acids (tRNA) and Related Compounds. XLIX. Solid-Phase Synthesis of Nonadecaribonucleotide Corresponding to the 5'-Half of the Formylmethionine tRNA Deficient in D-Loop and Stem Region

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概要

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• Ribooligonucleotides (nonamer, decamer and nonadecamer) were synthesized by the solid phase phosphotriester method using 2'-O-tetrahydrofuranyl nucleosides. These oligomers were designed in order to obtain E. coli tRNA^<Met>_f deficient in D-loop and D-stem and its analogs. Condensation was performed by using dimer blocks and the dimethoxytrityl group on the 5'-hydroxyl group was removed selectively by 1M ZnBr_2 without affecting the 2'-protection.

• 社団法人日本薬学会の論文
• 1985-10-25

著者

• 池原 森男

  Faculty of Pharmaceutical Sciences, Osaka University(Present address)

• 大塚 栄子

  Faculty of Pharmaceutical Sciences, Osaka University

• 松儀 実宏

  Faculty of Pharmaceutical Sciences, Osaka University

• 大塚 栄子

  Faculty Of Pharmaceutical Sciences Hokkaido University

• 森岡 弘志

  北海道大学 薬学部

• 山根 明男

  Faculty of Pharmaceutical Sciences, Osaka University

• 森岡 弘志

  Faculty of Pharmaceutical Sciences, Osaka University

• 山根 明男

  Faculty Of Pharmaceutical Sciences Osaka University

• 松儀 実宏

  Faculty Of Pharmaceutical Sciences Osaka University

• 池原 森男

  Faculty Of Pharmaceutical Sciences Osaka University

関連論文

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