Studies on Transfer Ribonucleic Acids and Related Compounds. VII. Synthesis and Properties of Cyclic Oligoadenylic Acids
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概要
- 論文の詳細を見る
N, 2'-O-Dibenzoyladenosine 3'-phosphate was polymerized using dicyclohexylcarbodiimide as the activating reagent to give linear and cyclic oligoadenylic acids. When 5'-O-monomethoxytrityl-N, 2'-O-dibenzoyladenosine 3'-phosphate was added as the chain terminator linear oligoadenylic acids were obtained as major products. Cyclic di- and triadenylic acids were also synthesized by cyclization of the corresponding linear oligonucleotides and were found to be sensitive to RNase M. Their CD spectra were measured in aqueous and methanolic solution.
- 公益社団法人日本薬学会の論文
- 1974-05-25
著者
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池原 森男
Faculty of Pharmaceutical Sciences, Osaka University(Present address)
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辻 彰
Faculty of Pharmaceutical Sciences
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大塚 栄子
Faculty Of Pharmaceutical Sciences Hokkaido University
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辻 彰
Faculty Of Pharmaceutical Sciences Osaka University
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池原 森男
Faculty Of Pharmaceutical Sciences Osaka University
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