Polynucleotides. XXXIV. Ultraviolet Absorption and Circular Dichroism of ApUpG Analogs containing Modified Adenosine Residues
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概要
- 論文の詳細を見る
Ultraviolet absorption and circular dichroism properties of ApUpG and its analogs in which the adenosine is modified are reported. The adenosine analogs include formycin (F), 8,5'-S-cycloadenosine (^sA), 8,2'-S-cycloadenosine (A^s), 8,5'-O-cycloadenosine (^oA), 8,2'-O-cycloadenosine (A^o), 8-bromoadenosine (Br-A) and 8-oxyadenosine (HO-A). S-and-O-Cyclonucleosides and F take torsion angles of anti type, while Br-A and HO-A assumed to take syn conformation in these analog trinucleotides. All analogs have very weak stacking interaction and show a tendency to form an aggregate at low temperature.
- 社団法人日本薬学会の論文
- 1976-08-25
著者
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上杉 晴一
横浜国立大学工学部
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上杉 晴一
Faculty Of Engineering Yokohama National University
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池原 森男
Faculty of Pharmaceutical Sciences, Osaka University(Present address)
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大塚 栄子
Faculty Of Pharmaceutical Sciences Hokkaido University
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名倉 猛夫
Faculty of Pharmaceutical Sciences, Osaka University
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名倉 猛夫
Faculty Of Pharmaceutical Sciences Osaka University
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池原 森男
Faculty Of Pharmaceutical Sciences Osaka University
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上杉 晴一
Faculty Of Pharmaceutical Sciences Osaka University
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