核酸の立体構造を決定する因子 : 特にグリコシド結合まわりのコンホメーションのらせんの巻き方に対する影響について
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概要
- 論文の詳細を見る
This review describes the conformations of nucleic acids and oligonucleotides containing cyclonucleoside residues. From the studies on the oligomers of cyclonucleosides, it was demonstrated that oligonucleotides having a high anti glycosidic conformation can make up a left-handed helical system in contrast to the right-handed helical system of natural nucleic acids. Other left-handed helical structures which have been recently discovered or proposed are also reviwed. It is concluded that the glycosidic conformation in the monomer unit of nucleic acids play an important role in determining the handedness of the helical structures.
- 社団法人日本薬学会の論文
- 1983-07-25
著者
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上杉 晴一
横浜国立大学工学部
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上杉 晴一
大阪大学薬学部
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上杉 精一
Faculty Of Pharmaceutical Sciences Osaka University
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上杉 晴一
Faculty Of Pharmaceutical Sciences Osaka University
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