Studies on Transfer Ribonucleic Acids and Related Compounds. XXVII. Linear and Cyclic Oligonucleotides obtained by Polymerization of Protected Ribonucleoside 3'-Phosphates
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概要
- 論文の詳細を見る
An improved method for the dicyclohexylcarbodiimide-catalyzed polymerization of protected ribonucleoside 3'-phosphates (Cp, Ap, Up or Gp) is described. The formation of 5'-O-pyridinium compounds was eliminated and various 5'-O-monomethoxytritylated protected homooligonucleotides could be rapidly isolated in reasonable yields. The isolation and purification of 3', 5'-cyclized oligonucleotides (cCpCp, cUp (Up)_n or cGpGp) are described.
- 公益社団法人日本薬学会の論文
- 1979-12-25
著者
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池原 森男
Faculty of Pharmaceutical Sciences, Osaka University(Present address)
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大塚 栄子
Faculty Of Pharmaceutical Sciences Hokkaido University
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中川 栄子
Faculty of Pharmaceutical Sciences, Osaka University
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MARKHAM ALEXANDERF.
Faculty of Pharmaceutical Sciences, Osaka University
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Markham Alexanderf.
Faculty Of Pharmaceutical Sciences Osaka University
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中川 栄子
Faculty Of Pharmaceutical Sciences Osaka University
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池原 森男
Faculty Of Pharmaceutical Sciences Osaka University
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