350-kDa Royal Jelly Glycoprotein (Apisin), Which Stimulates Proliferation of Human Monocytes, Bears the β1-3Galactosylated N-Glycan : Analysis of the N-Glycosylation Site(Biochemistry & Molecular Biology)
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概要
- 論文の詳細を見る
While doing a structural analysis of minor component N-glycans linked to 350-kDa royal jelly glycoprotein (RJGP), which stimulates the proliferation of human monocytes, we found that a Galβ1-3GlcNAcβ1-4Man unit occurs on the insect glycoprotein. The structure of the fluorescence-labeled N-glycan was analyzed by sugar component analysis, IS-MS, and ^1H-NMR. The structural analysis showed that the 350-kDa RJGP bears Galβ1-3GlcNAcβ1-4 (GlcNAcβ1-2)Manα1-3 (Manα1-3Manα1-6) Manβ1-4GlcNAcβ1-4GlcNAc, suggesting this insect glycoprotein is one of the substrates for both β1-3 galactosyl and β1-4 N-acetyl-glucosamininyl transferases. To our knowledge, this is the first report that succeeded in identifing an insect glycoprotein bearing the β1-3 galactosylated N-glycan.
- 社団法人日本農芸化学会の論文
- 2003-09-23
著者
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木村 吉伸
岡山大学農学部
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木村 吉伸
岡山大学 農
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Sugimoto Hiroyuki
Yamada Apiculture Center, Inc.
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YAMADA Hideo
Yamada Apiculture Center, Inc.
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KIMURA Yoshinobu
Department of Bioresources Chemistry, Faculty of Agriculture, Okayama University
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Yamada Hideyuki
SEIREN CO. LTD.
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木村 吉伸
Dep. Of Biofunctional Chemistry Graduate School Of Natural Sci. And Technol. Okayama Univ.
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Kimura Mariko
Faculty of Food Culture, Department of Nutrition, Kurashiki Sakuyo University
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Kuroyanagi M
Fac. Of Pharmaceutical Sciences At Kagawa Campus Tokushima Bunri Univ.
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木村 吉伸
岡山大学
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Kimura Mariko
Faculty Of Food Culture Department Of Food Systems Kurashiki Sakuyo University
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Yonekura Masami
Department of Applied Biological Resource Sciences, School of Agriculture, lbaraki University
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Kimura M
Laboratory Of Biochemistry Faculty Of Agriculture Graduate School Kyushu University
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OKIHARA Kiyoshi
Yamada Apiculture Center Inc.
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Yonekura Masami
Food Function Laboratory School Of Agriculture Ibaraki University
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Yamai Masafumi
Division Of Biomolecular Science The Graduate School Of Natural Science And Technology Okayama Unive
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Yonekura Masami
Faculty Of Agriculture Ibaraki University
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Yonekura Masami
Department Of Applied Biological Resource Science School Of Agriculture Ibaraki University
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Yonekura Masami
Department Of Applied Biological Resource Sciences School Of Agriculture Lbaraki University
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Kimura Yoshinobu
Department Of Agricultural Science Faculty Of Agriculture Okayama University
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Sugimoto Hiroyuki
Yamada Apiculture Center
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Yamada Hidenori
Department Of Bioengineering Science Faculty Of Engineering Okayama University
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Yamada H
Institute For Bee Products And Health Science Yamada Apiculture Center Inc.
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TSUMURA Kazunori
Department of Bioresources Chemistry, Faculty of Agriculture, Okayama University
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Kuroyanagi Masanori
Fac. Of Pharmaceutical Sciences At Kagawa Campus Tokushima Bunri Univ.
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Yamada Hisami
Laboratory Of Molecular Microbiology School Of Agriculture Nagoya University
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OKIHARA Kiyoshi
Institute for Bee Products and Health Science, Yamada Apiculture Center, Inc.
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Okihara K
Institute For Bee Products And Health Science Yamada Apiculture Center Inc.
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Kimura Mariko
Fac. Of Food Culture Dep. Of Nutrition Kurashiki Sakuyo Univ.
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Tsumura K
Department Of Bioresources Chemistry Faculty Of Agriculture Okayama University
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Okihara Kiyoshi
Institute For Bee Products And Health Science Yamada Apiculture Center Inc.
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Yamada Hideo
Institute For Bee Products And Health Science Yamada Apiculture Center Inc.
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Yamada Hideo
Yamada Apiculture Center Inc.
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