Effects of α- and β-Arbutin on Activity of Tyrosinases from Mushroom and Mouse Melanoma
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概要
- 論文の詳細を見る
The effects of α- and β-arbutin on the activity of tyrosinases from mushroom and mouse melanoma were examined. α-Arbutin was synthesized from hydroquinone and starch using glucoside synthetase (GSase). β-Arbutin inhibited both tyrosinase activities from mushroom and mouse melanoma. α-Arbutin inhibited only the tyrosinase from mouse melanoma, 10 times as strongly as β-arbutin. The IC_<50> of α-arbutin was 0.48 mM and its inhibitory mechanism was speculated to be mixed type inhibition, while that of β-arbutin was noncompetitive.
- 社団法人日本農芸化学会の論文
- 1995-01-23
著者
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Murao Sawao
Department of Agricultural Chemistry, College of Agriculture, University of Osaka Prefecture
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Murao S
Department Of Applied Biology Faculty Of Textile Science Kyoto Institute Of Technology
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Murao S
Department Of Applied Biological Chemistry College Of Agriculture University Of Osaka Prefecture
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Morikawa Shin-ya
School Of Pharmaceutical Sciences Nagasaki University
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SHIN Takashi
Department of Applied Microbial Technology, The Kumamoto Institute of Technology
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Murao S
Sojo Univ. Kumamoto Jpn
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Murao Sawao
Department Of Agricultural Chemistry College Of Agriculture University Of Osaka Prefecture
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Shin T
Department Of Applied Microbial Technology The Kumamoto Institute Of Technology
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Shin Takashi
Department Of Applied Microbial Technology Kumamoto Institute Of Technology
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YAMAMOTO Ryohei
Kurabo Industries Limited
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Funayama Masataka
Technical Research Laboratory, Kurabo Industries Ltd.
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Arakawa Hirokuni
Technical Research Laboratory, Kurabo Industries Ltd.
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Yamamoto Ryohei
Technical Research Laboratory, Kurabo Industries Ltd.
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Nishino Toyokazu
Technical Research Laboratory, Kurabo Industries Ltd.
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Nishino T
Technical Research Laboratory Kurabo Industries Ltd.
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Arakawa Hirokuni
Technical Research Laboratory Kurabo Industries Ltd.
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Takenisi Shigeyuki
Osaka Municipal Technical Research Institute
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Funayama Masataka
Technical Research Laboratory Kurabo Industries Ltd.
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MURAO SAWAO
Department of Applied Microbial Technology, Kumamoto Institute of Technology
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SHIN Takashi
Department of Agricultural Chemistry, College of Agriculture, University of Osaka Prefecture
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