Acetoxydehydroaustin, a New Bioactive Compound, and Related Compound Neoaustin from Penicillium sp. MG-11
スポンサーリンク
概要
- 論文の詳細を見る
Compounds from a soil isolate of Penicillium sp. MG-11 showed remarkable convulsive activity against silkworms. Activity-based fractionation of an acetone extract of the fermentation products resulted in the isolation of four compounds. One was identified as verruculogen, which was an active principle. Another compound, acetoxydehydroaustin, was new and was structurally characterized by spectral data and a single-crystal X-ray analysis. The two other compounds were identified as dehydroaustin and austin on the basis of the spectral data. Although the latter three compounds were not active themselves, they enhanced the convulsive activity of verruculogen in a silkworm bioassay. Three additional compounds with no identifiable activity were also isolated. Two of them were identified as austinol and dehydroaustinol, and the third was determined to be a new related compound named neoaustin by an X-ray analysis of crystals.
- 社団法人日本農芸化学会の論文
- 1994-02-23
著者
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HAYASHI Hideo
Deparment of Applied Biological Chemistry, College of Agriculture, Osaka Prefecture University
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Clardy J
Cornell Univ. New York
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Jon Clardy
Baker Laboratory Department Of Chemistry Cornell University
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Lee Y.
Department Of Zoology National University Of Singapore
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Hayashi H
Osaka Prefecture Univ. Osaka Jpn
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Clardy Jon
Department Of Chemistry Baker Laboratory Cornell University
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Clardy Jon
Department Of Chemistry And Chemical Biology Cornell University
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Mukaihara Manabu
Department of Agricultural Chemistry, College of Agriculture, University of Osaka Prefecture
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Murao Sawao
Department of Agricultural Chemistry, College of Agriculture, University of Osaka Prefecture
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Arai Motoo
Department of Agricultural Chemistry, College of Agriculture, University of Osaka Prefecture
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Murao S
Department Of Applied Biology Faculty Of Textile Science Kyoto Institute Of Technology
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Murao S
Department Of Applied Biological Chemistry College Of Agriculture University Of Osaka Prefecture
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Morikawa Shin-ya
School Of Pharmaceutical Sciences Nagasaki University
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Lee Y.
Department Of Geneticopathology Department Of Radiation Biology Research Institute For Nuclear Medic
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Arai M
Department Of Environmental Biology College Of Bioscience And Biotechnology Chubu University
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Arai Motoo
Department Of Agricultural Chemistry College Of Agriculture University Of Osaka Prefecture
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Murao S
Sojo Univ. Kumamoto Jpn
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Murao Sawao
Department Of Agricultural Chemistry College Of Agriculture University Of Osaka Prefecture
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Lee Y.
Department Of Anesthesiology Chang Gung Memorial Hospital Lin-kou Medical Center
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Mukaihara M
Mercian Corp. Fujisawa Jpn
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Lee Y.
Department Of Chemistry Cornell University
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MURAO SAWAO
Department of Applied Microbial Technology, Kumamoto Institute of Technology
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