New Dihydroquinolinone Toxic to Artemia salina Produced by Penicillium sp. NTC-47

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概要

• 論文の詳細を見る

• Penicillium sp. NTC-47, which had been isolated from a soil sample, produced novel dihydroquinolinones when cultured with okara (the insoluble residue of whole soybean). These metabolites, 1 and 2, were crystalline products with molecular formulas of C_<17>H_<17>NO_5 and C_<17>H_<17_>NO_4, respectively. The structure of 1 was established to be 3-methoxy-4, 5-dihydroxy-4-(4'-methoxyphenyl)-quinolinone by spectroscopic evidence and by an X-ray crystallographic analysis. Spectral data indicated the structure of 2 to be 5-deoxy-1. Compound 1 demonstrated toxicity against brine shrimp with an LC_<50> value of 20 μg/ml, but 2 exhibited no activity at a dose of 100 μg/ml.

• 社団法人日本農芸化学会の論文
• 1997-05-23

著者

• HAYASHI Hideo

  Deparment of Applied Biological Chemistry, College of Agriculture, Osaka Prefecture University

• Hayashi H

  Osaka Prefecture Univ. Osaka Jpn

• NAKAYAMA Mitsuru

  Department of Agricultural Chemistry, University of Osaka Prefecture

• NOZAKI Hiroshi

  Department of Biological Chemistry, Faculty of Science, Okayama University of Science

• NOZAKI Hiroshi

  National Institute for Resarch in Inorganic Materials

• INOUE Yoshiki

  Department of Obstetrics and Gynecology, Kinki University School of Medicine

• Nozaki H

  Okayama Univ. Sci. Okayama Jpn

• Nakayama M

  Juntendo Univ. School Of Medicine Tokyo Jpn

• Inoue Yoshiki

  Department Of Applied Biological Chemistry College Of Agriculture Osaka Prefecture University

• NAKATANI Tadashi

  Department of Applied Biological Chemistry, College of Agriculture, Osaka Prefecture University

• Nakatani T

  Department Of Applied Biological Chemistry College Of Agriculture Osaka Prefecture University

• Nakatani Tadashi

  Department Of Applied Biological Chemistry College Of Agriculture Osaka Prefecture University

• Nozaki Hiroshi

  Department Of Biochemistry Faculty Of Science Okayama University Of Science

• Nakayama Mitsuru

  Department Of Agricultural Chemistry College Of Agriculture University Of Osaka Prefecture

• Nozaki Hiroshi

  Department Of Biochemistry Faculty Of Science

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