Regulatory Effects of Purine and Pyrimidine Nucleoside 5-Di(tri)-phosphate-3-diphosphates on Eucaryote Protein Synthesis
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概要
- 論文の詳細を見る
Adenosine-, guanosine-, cytidine- and uridine-5-di(tri)-phosphate-3-diphosphates were enzymatically prepared by the use of Streptomyces adephospholyticus ATP nucleotide pyrophosphokinase (E.C. 2.7.6.4). Their regulatory effects were then investigated on translation of rat liver, rabbit globin and silkworm pupae chorion mRNAsby the wheat germ lysate system in vitro. They were found to exert base-specific and mRNA species-specific stimulatory or inhibitory effects, respectively. In particular, cytidine 5-diphosphate-3-diphosphate stimulated chorion mRNA translation 3-fold. The significance and limitations of the findings were discussed in relation to natural occurrence and possible regulatory functions of the nucleotides in eucaryotes.
- 社団法人 日本農芸化学会の論文
著者
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Mukai Jun-ichiro
Department Of Agricultural Chemistry And Graduate School Of Genetic Resources Technology Kyushu Univ
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Murao Sawao
Department Of Agricultural Chemistry College Of Agriculture University Of Osaka Prefecture
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Nishino Toyokazu
Department Of Agricultural Chemistry College Of Agriculture University Of Osaka Prefecture
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MURAO Sawao
Department of Agricultural Chemistry, The University of Osaka Prefecture
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FURUICHI Masato
Department of Agricultural Chemistry, Kyushu University
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