Evaluation of Intestinal Dioxin Permeability Using Human Caco-2 Cell Monolayers
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概要
- 論文の詳細を見る
A system to evaluate the intestinal permeability for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) was constructed with human intestinal Caco-2 cell monolayers. TCDD was added to the apical side of the cell monolayers and the basal TCDD concentration was estimated by using a HepG2 cell having a luciferase vector with a xenobiotic-responsive element in the promoter region. Addition of such food substances as chlorophyll to the apical side of the Caco-2 cell monolayers markedly decreased the apical-to-basal transport of TCDD. This system would be useful for use in searching for the materials having an inhibitory activity to intestinal TCDD absorption.
- 社団法人 日本食品科学工学会の論文
- 2003-11-01
著者
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SATSU Hideo
Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The U
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SHIMIZU Makoto
Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The U
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SATO Ryuichiro
Department of Applied Biological Chemistry, Graduate School of Agriculture and Life Sciences, The Un
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Satsu Hideo
Department Of Applied Biological Chemistry Division Of Agricultural And Life Sciences The University
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Sato R
Univ. Tokyo Tokyo Jpn
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Shimizu M
Univ. Tokyo Tokyo Jpn
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Ashida H
Department Of Biofunctional Chemistry Faculty Of Agriculture Kobe University
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Ashida Hitoshi
Department Of Agricultural Chemistry Kobe University
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Ashida Hitoshi
Graduate School Of Science & Technology Division Of Life Science Kobe University
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Tukey Robert
Department Of Chemistry Biochemistry & Pharmacology University Of California
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WATANABE Hirohito
Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Science, The Un
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Watanabe Hirohito
Department Of Life Science Meiji University
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Watanabe Hirohito
Department Of Applied Biological Chemistry Graduate School Of Agricultural And Life Science The Univ
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Shimizu Makoto
Graduate School Of Agricultural And Life Sciences The Univ. Of Tokyo
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NATSUME Yayoi
Department of Applied Biological Chemistry, The University of Tokyo
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HATSUGAI Yasuo
Department of Applied Biological Chemistry, The University of Tokyo
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Ashida Hitoshi
Department Of Life Science Graduate School Of Science And Technology Kobe University
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Satsu Hideo
Dep. Of Applied Biological Chemistry Graduate School Of Agricultural And Life Sciences The Univ. Of
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Satsu H
Univ. Tokyo Tokyo Jpn
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Sato Ryuichiro
Dep. Of Applied Biological Chemistry Graduate School Of Agriculture And Life Sciences Univ. Of Tokyo
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Ashida Hitoshi
Res. Center For Food Safety And Security Graduate School Of Agricultural Sci. Kobe Univ.
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Hatsugai Yasuo
Department Of Applied Biological Chemistry The University Of Tokyo
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Sato R
Department Of Applied Biological Chemistry The University Of Tokyo
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Sato Ryuichiro
Department Of Applied Biological Chemistry Graduate School Of Agricultural And Life Sciences The Uni
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Shimizu M
Department Of Applied Biological Chemistry Graduate School Of Agricultural And Life Sciences The Uni
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Ashida Hitoshi
Graduate School Of Agricultural Science Kobe University
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Natsume Yayoi
Department Of Applied Biological Chemistry Graduate School Of Agricultural And Life Sciences The Uni
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Sato Ryuichiro
Laboratory Of Biochemistry And Molecular Biology Graduate School Of Pharmaceutical Sciences Osaka Un
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Shimizu Makoto
Department Of Applied Biological Chemistry The University Of Tokyo
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Shimizu Makoto
Department Of Applied Biological Chemistry Graduate School Of Agricultural And Life Sciences The Uni
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Shimizu Makoto
Department Of Agricultural Chemistry Faculty Of Engineering The University Of Tokyo
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SATO Ryuichiro
Department of Agricultural Chemistry, The University of Tokyo
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