Modulation of the Intestinal Ca^<2+> Uptake by a Cheese Whey Protein Digest
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概要
- 論文の詳細を見る
We have previously constructed a system which enables the search for factors that could modulate the intestinal calcium transporter, CaT1 (TRPV6; Takano et al., Cytotechnology, 43, 113 (2003)). This system evaluates the CaT1-mediated calcium uptake by using CHO cells stably expressing human CaT1 (CHO-hCaT1 cells). We found that a cheese whey protein digest (CWP-D) increased the calcium uptake by the CHO-hCaT1 cells. CWP-D also enhanced the calcium uptake in human intestinal Caco-2 cells. The in vivo effects of CWP-D were then measured by using rats with enteral feeding. Although enteral feeding decreased the portal calcium concentration, CWP-D partially suppressed the decrease, suggesting that CWP-D could be used for food to enhance calcium absorption.
- 社団法人 日本農芸化学会の論文
- 2007-06-23
著者
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SATSU Hideo
Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The U
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SHIMIZU Makoto
Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The U
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SATO Ryuichiro
Department of Applied Biological Chemistry, Graduate School of Agriculture and Life Sciences, The Un
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Satsu Hideo
Department Of Applied Biological Chemistry Division Of Agricultural And Life Sciences The University
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Shimizu M
Univ. Tokyo Tokyo Jpn
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Satsu Hideo
Dep. Of Applied Biological Chemistry Graduate School Of Agricultural And Life Sciences The Univ. Of
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Satsu H
Univ. Tokyo Tokyo Jpn
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Sato Ryuichiro
Dep. Of Applied Biological Chemistry Graduate School Of Agriculture And Life Sciences Univ. Of Tokyo
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Sato R
Department Of Applied Biological Chemistry The University Of Tokyo
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Sato Ryuichiro
Department Of Applied Biological Chemistry Graduate School Of Agricultural And Life Sciences The Uni
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Shimizu M
Department Of Applied Biological Chemistry Graduate School Of Agricultural And Life Sciences The Uni
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Yoshikawa Yukako
School Of Human Environmental Sciences Mukogawa Women's University
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TAKANO Yoshihiko
Product Research & Development Department, Nippon Milk Community Co., Ltd.
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MATSUURA Toshiki
School of Human Environmental Sciences, Mukogawa Women's University
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Matsuura Toshiki
School Of Human Environmental Sciences Mukogawa Women's University
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Sato Ryuichiro
Laboratory Of Biochemistry And Molecular Biology Graduate School Of Pharmaceutical Sciences Osaka Un
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Shimizu Makoto
Department Of Applied Biological Chemistry The University Of Tokyo
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Takano Yoshihiko
Product Research & Development Department Nippon Milk Community Co. Ltd.
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Shimizu Makoto
Department Of Agricultural Chemistry Faculty Of Engineering The University Of Tokyo
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SATO Ryuichiro
Department of Agricultural Chemistry, The University of Tokyo
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