Synthesis of Novel Heterobranched β-Cyclodextrins Having β-D-N-Acetylglucosaminyl-Maltotriose on the Side Chain
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概要
- 論文の詳細を見る
From a mixture of N-acetylglucosaminyl-β-cyclodextrin (GlcNAc-βCD) and lactose, β-D-galactosyl-GlcNAc-βCD (Gal-GlcNAc-βCD) was synthesized by the transfer action of β-galactosidase. GlcNAc-maltotriose (Glc3) and Gal-GlcNAc-Glc3 were produced with hydrolysis of GlcNAc-βCD by cyclodextrin glycosyltransferase, and Gal-GlcNAc-βCD by bacterial saccharifying α-amylase respectively. Finally, GlcNAc-Glc3-βCD and Gal-GlcNAc-Glc3-βCD were synthesized in 5.2% and 3.5% yield when Klebsiella pneumoniae pullulanase was incubated with the mixture of GlcNAc-Glc3 and βCD, or Gal-GlcNAc-Glc3 and βCD respectively. The structures of GlcNAc-Glc3-βCD and Gal-GlcNAc-Glc3-βCD were analyzed by FAB-MS and NMR spectroscopy and identified as 6-O-α-(63-O-β-D-N-acetylglucosaminyl-maltotriosyl)-βCD, and 6-O-α-(4-O-β-D-galactopyranosyl-63-O-β-D-N-acetylglucosaminyl-maltotriosyl)-βCD respectively.
- 社団法人 日本農芸化学会の論文
- 2005-04-23
著者
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Murakami Hiromi
Osaka Municipal Technical Res. Inst.
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TANIMOTO Toshiko
School of Pharmaceutical Sciences Mukogawa Women's University
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Murakami H
Laboratory Of Cellular Regulation Technology Graduate School Of Genetic Resources Technology Kyushu
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NAKANO HIROFUMI
Osaka Municipal Technical Research Institute, and Yashiro Co, Ltd.,
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Kitahata S
Department Of Bioscience And Biotecnology Shinshu University
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OMATSU Mizue
School of Pharmaceutical Sciences, Mukogawa Women's University
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IKUTA Akiko
School of Pharmaceutical Sciences, Mukogawa Women's University
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NISHI Yuki
School of Pharmaceutical Sciences, Mukogawa Women's University
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KITAHATA Sumio
Department of Bioscience and Biotecnology, Shinshu University
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Nishi Yuki
School Of Pharmaceutical Sciences Mukogawa Women's University
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Ikuta Akiko
School Of Pharmaceutical Sciences Mukogawa Women's University
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Omatsu Mizue
School Of Pharmaceutical Sciences Mukogawa Women's University
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Kitahata Sumio
Department Of Bioscience And Biotechnology Faculty Of Agriculture Shinshu University
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Murakami H
Osaka Municipal Technical Res. Inst.
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Kobayashi S
Fukui Univ. Technol. Fukui Jpn
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Nakano H
Department Of Biochemistry Osaka Municipal Technical Research Institute
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Tanimoto T
School Of Pharmaceutical Sciences Mukogawa Women's University
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Tanimoto Toshiko
School Of Pharmaceutical Science Mukogawa Women's University
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Nakano H
Kyoto Prefectural Univ. Kyoto Jpn
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Nishi Yuki
School Of Pharmaceutical Sciences Mukogawa Women's Univ.
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Nakano Hirofumi
Osaka Municipal Technical Research Institute
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Nakano Hirofumi
Department Of Chemistry Faculty Of Science Osaka University
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