UCH9, a New Antitumor Antibiotic Produced by Streptomyces: I. Producing Organism, Fermentation, Isolation and Biological Activities

スポンサーリンク

概要

• 論文の詳細を見る
• 1998-03-25

著者

• Akiyama T

  Pharmaceutical Research Institute Kyowa Hakko Kogyo Co. Ltd.

• Chiba S

  Kyowa Hakko Kogyo Co. Ltd. Yamaguchi Jpn

• OGAWA Harumi

  Tokyo Research Laboratories, Kyowa Hakko Kogyo Co., Ltd.

• YAMASHITA Yoshinori

  Tokyo Research Laboratories, Kyowa Hakko Kogyo Co., Ltd.

• KATAHIRA Ritsuko

  Tokyo Research Laboratories, Kyowa Hakko Kogyo Co., Ltd.

• CHIBA Shigeru

  Tokyo Research Laboratories, Kyowa Hakko Kogyo Co., Ltd.

• IWASAKI Toshiaki

  Pharmaceutical Research Laboratories, Kyowa Hakko Kogyo Co., Ltd.

• ASHIZAWA Tadashi

  Pharmaceutical Research Laboratories, Kyowa Hakko Kogyo Co., Ltd.

• NAKANO Hirofumi

  Tokyo Research Laboratories, Kyowa Hakko Kogyo Co., Ltd.

• Iwasaki Toshiaki

  Pharmaceutical Research Laboratories Kyowa Hakko Kogyo Co. Ltd.

• Ogawa Harumi

  Tokyo Research Laboratories Kyowa Hakko Kogyo Co. Ltd.

• Chiba S

  Tokyo Research Laboratories Kyowa Hakko Kogyo Co. Ltd.

• Yamashita Yoshinori

  Pharmaceutical Research Center, Kyowa Hakko Kogyo Co., Ltd.

• Ashizawa Tadashi

  Tokyo Research Laboratories Kyowa Hakko Kogyo Co. Ltd.

• Ogawa H

  Tokyo Research Laboratories Kyowa Hakko Kogyo Co. Ltd.

• Yamashita Yoshinori

  Tokyo Research Laboratories Kyowa Hakko Kogyo Co. Ltd.

• Yamashita Yoshinori

  Pharmaceutical Research Center Kyowa Hakko Kogyo Co. Ltd.

• Katahira Ritsuko

  Tokyo Research Laboratories Kyowa Hakko Kogyo Co. Ltd.

• Ashizawa Tadashi

  Pharmaceutical Research Institute Kyowa Hakko Kogyo Co. Ltd.

• Chiba Shigeru

  Tokyo Research Laboratories Kyowa Hakko Kogyo Co. Ltd.

• Nakano Hirofumi

  Department Of Chemistry Faculty Of Science Osaka University

• Nakano Hirofumi

  Tokyo Research Laboratories Kyowa Hakko Kogyo Co. Ltd.

関連論文

• Early Diagnosis of Central Nervous System Aspergillosis with Combination Use of Cerebral Diffusion-weighted Echo-planar Magnetic Resonance Image and Polymerase Chain Reaction of Cerebrospinal Fluid
• Ischemic Colitis as a Manifestation of Thrombotic Microangiopathy Following Bone Marrow Transplantation
• Rapid progression of chronic myelomonocytic leukemia following diaminodiphenyl sulphone treatment for dermatitis herpetiformis
• Gain-of-function mutations and copy number increases of Notch2 in diffuse large B-cell lymphoma
• Acute eosinophilic pneumonia is a non-infectious lung complication after allogeneic hematopoietic stem cell transplantation
• Molecular and cytogenetic response of chronic myelogenous leukemia treated with imatinib mesylate : one institutional experience in Japan
• Late-onset pneumatosis cystoides intestinalis associated with non-infectious pulmonary complications after allogeneic hematopoietic stem cell transplantation
• Herpes simplex encephalitis and subsequent cytomegalovirus encephalitis after chemoradiotherapy for central nervous system lymphoma : a case report and literature review
• ESHAP therapy effective in a patient with Langerhans cell sarcoma
• Clinical features of late cytomegalovirus infection after hematopoietic stem cell transplantation
• A case of adult Langerhans cell histiocytosis showing successfully regenerated osseous tissue of the skull after chemotherapy
• Immunotherapy against metastatic renal cell carcinoma with mature dendritic cells
• EI-1507-1 and-2, Novel Interleukin-1βConverting Enzyme Inhibitors Produced by Streptomyces sp. E-1507
• UCH9, a New Antitumor Antibiotic Produced by Streptomyces: I. Producing Organism, Fermentation, Isolation and Biological Activities
• UCE6, a New Antitumor Antibiotic with Topoisomerase I-mediated DNA Cleavage Activty Produced by Actinomycetes: Producing Organism, Fermentation, Isolation and Biological Activity
• Splenic Peliosis in a Patient with Aplastic Anemia during Danazol Therapy
• Enrichment of Ethyl Docosahexaenoate by Selective Alcoholysis with Immobilized Rhizopus delemar Lipase
• Fatty Acid Specificity of Rhizopus delemar Lipase in Acidolysis
• Inhibition of β-Fructofuranosidases and α-Glucosidases by Synthetic Thio-fructofuranoside(Biochemistry & Molecular Biology)
• Enzymatic Synthesis of N-Acetylglucosaminyl-cyclodextrin by the Reverse Reaction of N-Acetylhexosaminidase from Jack Bean
• Acceptor Specificity of Cyclodextrin Glycosyltransferase from Bacillus stearothermophilus and Synthesis of α-D-Glucosyl O-β-D-galactosyl-(1→4)-β-D-glucoside
• Pyrronamycin A and B, Novel Antitumor Antibiotics Containing Pyrrole-amide Repeating Unit, Produced by Streptomyces sp.
• UCT1072s, New Antitumor Antibiotics with Topoisomerase II Mediated DNA Cleavage Activity, from Aspergillus sp.
• RES-701-2,-3 and-4, Novel and Selective Endothelin Type B Receptor Antagonists Produced by Streptomyces sp.I.Taxonomy of Producing Strains, Fermentation, Isolation, and Biochemical Properties
• Synthesis of Novel Heterobranched β-Cyclodextrins Having β-D-N-Acetylglucosaminyl-Maltotriose on the Side Chain
• Synthesis of Glycosyl Glycerol by Cyclodextrin Glucanotransferases(ENZYMOLOGY,PROTEIN ENGINEERING,AND ENZYME TECHNOLOGY)
• Hydrolysis of β-Glucosyl Ester Linkage of p-Hydroxybenzoyl β-D-Glucose, a Chemically Synthesized Glucoside, by β-Glucosidases
• Synthesis of Novel Heterobranched β-Cyclodextrins from α-D-Mannosyl Maltotriose and β-Cyclodextrin by the Reverse Action of Pullulanase, and Isolation and Characterization of the Products
• Hydrolysis of β-Galactosyl Ester Linkage by β-Galactosidases
• Transfructosylation of Thiol Group by β-Fructofuranosidases
• Synthesis of Novel Heterobranched β-Cyclodextrins from 4^2-O-β-D-Galactosyl-Maltose and β-Cyclodextrin by the Reverse Action of Pullulanase, and Isolation and Characterization of the Products
• Galactosylation of Thiol Group by β-Galactosidase
• Purification and Some Properties of a β-Glucosidase from Flavobacterium johnsonae
• Purification and Characterization of a Novel β-Glucosidase from Clavibacter michiganense That Hydrolyzes Glucosyl Ester Linkage in Steviol Glycosides
• Enzymatic Synthesis of Oligosaccharides Containing Galβ→4Gal Disaccharide at the Non-Reducing End Using β-Galactanase from Penicillium citrinum
• Enzymatic Synthesis of Mannosyl-cyclodextrin by α-Mannosidase from Jack Bean
• Synthesis of 2-Deoxy-glucooligosaccharides through Condensation of 2-Deoxy-D-glucose by Glucoamylase and α-Glucosidase
• Esterification of Glycosides by a Mono- and Diacylglycerol Lipase from Penicillium camembertii and Comparison of the Products with Candida cylindracea Lipase
• Evaluation of Chiral Amino Acid Discrimination by a Permethylated Cyclic Tetrasaccharide, cyclo-{→6)-α-D-Glcp-(1→3)-α-D-Glcp-(1→6)-α-D-Glcp-(1→3)-α-D-Glcp-(1→}, Using FAB Mass Spectrometry
• Acceptor Specificities of α-Mannosidases from Jack Bean and Almond, and Trans-mannosylation of Branched Cyclodextrins
• GEX1 Compounds, Novel Antitumor Antibiotics Related to Herboxidiene, Produced by Streptomyces sp. : II. The Effects on Cell Cycle Progression and Gene Expression
• GEX1 Compounds, Novel Antitumor Antibiotics Related to Herboxidiene, Produced by Streptomyces sp. : I. Taxonomy, Production, Isolation, Physicochemical Properties and Biological Activities
• GE3, a Novel Hexadepsipeptide Antitumor Antibiotic, Produced by Streptomyces sp. I. Taxonomy, Production, Isolation, Physico-chemical Properties, and Biological Activities
• Terpentecin and UCT4B, New Family of Topoisomerase II Targeting Antitumor Antibiotics Produced by Streptomyces:Producing Organism, Fermentation and Large Scale Purification
• P-241 EH21A1〜A4, benzenoid ansamycins, a new class of anti-tumor agents with conformational significance for Hsp90 inhibitory activity
• Synthesis and Anti-tubulin Activity of Ustiloxin D Derivatives
• Isolation and Structure of an Antimitotic Cyclic Peptide, Ustiloxin F: Chemical Interrelation with a Homologous Peptide, Ustiloxin B
• MPC1001, a New Antitumor Antibiotic Produced by Cladorrhinum sp
• Chrolactomycin, a Novel Antitumor Antibiotic Produced by Streptomyces sp.
• UCS1O25A, a Novel Antibiotic Produced by Acremonium sp.
• GE3, a Novel Hexadepsipeptide Antitumor Antibiotic Produced by Streptomyces sp. II. Structure Determination
• Dual antitumor mechanisms of Notch signaling inhibitor in a T-cell acute lymphoblastic leukemia xenograft model
• Purification and Characterization of a Novel α-Glucuronidase from Aspergillus niger Specific for O-α-D-Glucosyluronic Acid α-D-Glucosiduronic Acid
• Production of Structured Lipid Containing Docosahexaenoic and Caprylic Acids Using Immobilized Rhizopus delemar Lipase
• EI-2128-1, a Novel Interleukin-1βConverting Enzyme Inhibitor Produced by Penicillium sp. E-2128
• RP-1776, a Novel Cyclic Peptide Produced by Streptomyces sp., Inhibits the Binding of PDGF to the Extracellular Domain of Its Receptor
• The Clecarmycins, New Antitumor Antibiotics Produced by Streptomyces:Fermentation, Isolation and Biological Properties
• Mouse N-Acetylgalatosamine 4-Sulfotransferases-1 and -2. Molecular Cloning, Expression, Chromosomal Mapping and Detection of Their Activity with GalNAcβ1-4GlcNAcβ1-octyl
• Synthesis of 2-acetamido-2-deoxy-3-O-sulfonato-D-galactopyranose sodium salt
• Belactosin A, a Novel Antitumor Antibiotic Acting on Cyclin/CDK Mediated Cell Cycle Regulation, Produced by Streptomyces sp.
• Lipase-Catalyzed Esterification of Mono- and Oligoglycosides with Various Fatty Acids
• MS-444, a New Inhibitor of Myosin Light Chain Kinase from Micromonospora sp.KY7123
• Syntheses of Glucosides with Trimethylolpropane and Two Related Polyol Moieties by Cyclodextrin Glucanotransferase and Their Esterification by Lipase
• Characterization of Dimers of Hydroquinone Glucosides Produced by Peroxidase-Catalyzed Polymerization
• SYNTHESIS OF MITOMYCIN DERIVATIVES WITH DISULFIDE AT THE 7-N SIDE CHAIN (3). SYNTHESIS OF KW2149 AND STRUCTURE-ACTIVITY RELATIONSHIPS AMONG MITOMYCIN DERIVATIVES WITH DISULFIDE AT THE 7-N SIDE CHAIN
• Purification and Some Properties of a New Levanase from Bacillus sp. No. 71
• Purification and Some Properties of a Trehalase from a Green Alga, Lobosphaera sp.
• Purification and Characterization of a Carbohydrate : Acceptor Oxidoreductase from Paraconiothyrium sp. That Produces Lactobionic Acid Efficiently
• UCH9, a New Antitumor Antibiotic Produced by Streptomyces II. Structure Elucidation of UCH9 by Mass and NMR Spectroscopy
• Formation of Trehalose and Its 2-Deoxy Analogs through Condensation by a Trehalase from Lobosphaera sp.
• The Rhodium(II) Acetate- Catalyzed Reaction of Alkenyl and Alkynyl α-Diazoacetates with Thioketene
• Optimization of Lactobionic Acid Production by Acetobacter orientalis Isolated from Caucasian Fermented Milk, "Caspian Sea Yogurt"

もっと見る 閉じる

スポンサーリンク