THE FIRST EXAMPLES OF ISOLATED N-UNSUBSTITUTED 1H-1,4-BENZODIAZEPINES(Communications to the Editor)

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概要

• 論文の詳細を見る

• The photolysis in the presence of sodium methoxide of-the 4-azidoquirnolines (5a-g) having a carbonyl group or its analogue in the 2- or 8-position resulted in ring expansion to give the stable N-unsubstituted 1H-1,4-benzodiazepines (6a-g). These were assumed to be stabilized by intramolecular hydrogen bonding between the NH and the 2- or 9-acyl groups. It is known that the N-unsubstituted 1H-1,4-benzodiazepines having no acyl group are too unstable to be isolated.

• 公益社団法人日本薬学会の論文
• 1987-11-25

著者

• 土屋 隆

  Faculty of Pharmaceutical Sciences, Hokuriku University

• 土屋 隆

  School of Pharmacy, Hokuriku University

• 指田 春喜

  School of Pharmacy, Hokuriku University

• 指田 春喜

  北陸大学薬学部

• 指田 春喜

  Faculty Of Pharmaceutical Sciences Hokuriku University

• 土屋 隆

  Faculty Of Pharmaceutical Sciences Hokuriku University

• 要 衛

  School of Pharmacy, Hokuriku University

• 要 衛

  北陸大学薬学部

• 要 衛

  Faculty Of Pharmaceutical Sciences Of Hokuriku University

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