Studies on Diazepines. XIV. Photolysis of Thieno-, Furo-, and Pyrrolo-[c] pyridine N-Imides : Formation of Novel Fused 1H-1,3- and 3H-2,3-Diazepines

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概要

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• Irradiation of the methylpyridine N-imides (3b-g) condensed with a thiophene, furan, or pyrrole ring on the c-side of the pyridine ring gave the corresponding novel fused 1H-1,3-(5) and/or 3H-2,3-diazepines (6), together with the aminopyridines (7) and the parent fused pyridines (1), whereas the fused pyridine N-imide (3a) having no methyl group gave only the aminopyridine derivative (4). This photolysis may proceed by rearrangement to two kinds of diaziridine intermediates, (8) and (9) ; the latter may give the 2,3-diazepines (6) directly by ring-expansion, whereas the former may further rearrange to the aziridine intermediate (10), followed by ring-expansion to give the 1,3-diazepines (5). Some reactions of the diazepines (5 and 6) thus obtained were also examined.

• 社団法人日本薬学会の論文
• 1981-06-25

著者

• 沢西 啓之

  Faculty Of Pharmaceutical Sciences Hokuriku University

• 沢西 啓之

  School of Pharmacy, Hokuriku University

• 土屋 隆

  School of Pharmacy, Hokuriku University

• 円角 美智子

  School of Pharmacy, Hokuriku University

• 平井 豊子

  School of Pharmacy, Hokuriku University

• 土屋 隆

  Faculty Of Pharmaceutical Sciences Hokuriku University

• 平井 豊子

  School Of Pharmacy Hokuriku University

• 円角 美智子

  School Of Pharmacy Hokuriku University

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