Studies on Diazepines. XXIII. : Reactions of Monocyclic 1H-1,3-Diazepines. (1). : Cycloaddition Reaction with 2,5-Dimethyl-3,4-diphenylcyclopentadienone

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概要

• 論文の詳細を見る

• The thermal cycloaddition reaction of 1-ethoxycarbonyl-1H-1,3-diazepines (4a, b) with 2,5-dimethyl-3,4-diphenylcyclopentadienone (5) gave three kinds of 1 : 1 cycloadducts, exo [6+4]π (6), syn-endo [4+2]π (7), and anti-endo [4+2]π (8) cycloadducts, the structures of which were elucidated by spectral analyses and the following photochemical study. Irradiation of the [4+2]π cycloadducts 7 and 8 resulted in an intramolecular [2+2]π cycloaddition to afford the cage compounds 12 and 13,respectively, while the [6+4]π cycloadducts (6), upon irradiation, underwent a retro-reaction to give the bicyclic compounds (11), presumably via the parent 1,3-diazepines (4).

• 公益社団法人日本薬学会の論文
• 1986-11-25

著者

• 土屋 隆

  Faculty of Pharmaceutical Sciences, Hokuriku University

• 土屋 隆

  School of Pharmacy, Hokuriku University

• 栗田 城治

  School of Pharmacy, Hokuriku University

• 栗田 城治

  Faculty of Pharmaceutical Sciences, Hokuriku University

• 土屋 隆

  Faculty Of Pharmaceutical Sciences Hokuriku University

• 小島 弘一

  School of Pharmacy, Hokuriku University

• 栗田 城治

  Faculty Of Pharmaceutical Sciences Hokuriku University

• 小島 弘一

  School Of Pharmacy Hokuriku University

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