PHOTOLYSIS OF PYRIDYL AZIDES IN THE PRESENCE OF METHOXIDE IONS : FORMATION OF FULLY UNSATURATED 1,3- AND 1,4-DIAZEPINES

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概要

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• Photolysis of 4-azidopyridines (1) in the presence of methoxide ions resulted in ring-expansion to give the 6H-1,4-diazepines (4). Treatment of the diazepine (4a) with benzoyl chloride afforded the 1-benzoyl-1H-1,4-diazepine (5), whose structure was confirmed by some thermal reactions. Upon irradiation under similar conditions, 3-azidopyridines (10) gave the 5H-1,3-diazepines (13), but no 1,4-diazepines could be obtained. Treatment of the diazepines (13) with benzoyl chloride resulted in the formation of the 5-benzoylamino-2-methoxypyridines (16), presumably via the 1-benzoyl-1H-1,3-diazepines (14).

• 社団法人日本薬学会の論文
• 1984-11-25

著者

• 沢西 啓之

  Faculty Of Pharmaceutical Sciences Hokuriku University

• 沢西 啓之

  School of Pharmacy, Hokuriku University

• 土屋 隆

  School of Pharmacy, Hokuriku University

• 田島 加代子

  School of Pharmacy, Hokuriku University

• 長田 真

  School of Pharmacy, Hokuriku University

• 長田 真

  School Of Pharmacy Hokuriku University

• 土屋 隆

  Faculty Of Pharmaceutical Sciences Hokuriku University

• 田島 加代子

  北陸大学 薬

関連論文

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