Studies on Seven-Membered Heterocycles.XXXIII. : Synthesis of Fully Unsaturated 1,2,5-Triazepines by Photochemical Ring Expansion of 4-Azidopyridazines
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概要
- 論文の詳細を見る
Photolysis of the 3-methoxy-4-azidopyridazines (11) in the presence of a base such as methoxide ion and diethylamine resulted in ring-expansion to produce the 1H-1,2,5-triazepines (12 and 27), which were too unstable to be isolated, but tautomerized to the stable 4H-isomers (13 and 28) on further treatment with sodium methoxide and were converted to the stable 1-acetyl-1H-1,2,5-triazepines (14 and 29) by acetylation with acetyl chloride. The products 12-14 and 27-29 are the first examples of fully unsaturated 1,2,5-triazepines and were characterized by means of spectral analyses and some chemical reactions.
- 社団法人日本薬学会の論文
- 1990-11-25
著者
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斉藤 秀一
Faculty Of Pharmaceutical Sciences Hokuriku University
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沢西 啓之
Faculty Of Pharmaceutical Sciences Hokuriku University
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土屋 隆
Faculty of Pharmaceutical Sciences, Hokuriku University
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土屋 隆
Faculty Of Pharmaceutical Sciences Hokuriku University
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