Studies on Diazepines. IX. Difference between Photochemical and Thermal Rearrangements of 3H-1,2-Benzodiazepines into 3-Vinylindazoles

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概要

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• The thermolysis of the 3-substituted 3H-1,2-benzodiazepines (1) afforded 1 : 1 mixtures of trans- (2) and cis- (3) 3-vinylindazoles, whereas their photolysis gave only the transisomers (2). The 3-substituted 5-methyl-3H-1,2-benzodiazepines (4) gave similar results. These findings suggest that the thermolysis occurs in a stepwise manner via the diradical intermediate (9), whereas the photolysis proceeds in a concerted manner.

• 公益社団法人日本薬学会の論文
• 1979-10-25

著者

• 土屋 隆

  School of Pharmacy, Hokuriku University

• 栗田 城治

  School of Pharmacy, Hokuriku University

• 栗田 城治

  Faculty of Pharmaceutical Sciences, Hokuriku University

• 土屋 隆

  Faculty Of Pharmaceutical Sciences Hokuriku University

• 栗田 城治

  Faculty Of Pharmaceutical Sciences Hokuriku University

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