Studies on Nucleosides and Nucleotides. LXXXIX. Purine Cyclonucleosides. (43). Synthesis and Properties of 2'-Halogeno-2'-deoxyguanosines
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概要
- 論文の詳細を見る
The reaction of N^2-isobutyryl-9-(2'-O-trifluoromethanesulfonyl-3', 5'-di-O-tetrahydrofuranyl-β-D-arabinofuranosyl) guanine with tetra-n-butylammonium fluoride or an appropriate metal halide in dimethylformamide aftorded N^2-isobutyryl-3', 5'-di-O-tetrahydrofuranyl-2'-halogeno-2'-deoxyguanosines. The deprotection of these products led to 2'-halogeno-2'-deoxyguanosines. The ultraviolet absorption properties, ^1H and ^<13>C nuclear magnetic resonance spectral properties of the products were recorded.
- 公益社団法人日本薬学会の論文
- 1981-11-25
著者
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池原 森男
Faculty Of Pharmaceutical Sciences Osaka University
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伊村 純子
Faculty of Pharmaceutical Sciences, Osaka University
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伊村 純子
Faculty Of Pharmaceutical Sciences Osaka University
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