The Effect of a Cystamine Derivative, Bis[2-(E-2-hexenoylamino)ethyl] Disulfide, on Rat Platelet Aggregation
スポンサーリンク
概要
- 論文の詳細を見る
Bis[2-(E-2-alkenoylamino)ethyl] disulfides (compds. I), synthesized from cystamine and 2-trans fatty acids, inhibited collagen-induced rat and rabbit platelet aggregation. The most potent compound was bis[2-(E-2-hexenoylamino)ethyl] disulfide (compd. I-1), and this compound suppressed thromboxane B_2 formation from arachidonic acid in rat platelets. The results suggested that compd. I-1 has an inhibitory effect on cyclooxygenase.
- 社団法人日本薬学会の論文
- 1989-07-25
著者
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小濱 靖弘
大阪大学 薬 微薬品化
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辻川 和丈
阪大薬
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小濱 靖弘
Faculty of Pharmaceutical Sciences, Osaka University
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辻川 和丈
Faculty of Pharmaceutical Sciences, Osaka University
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三村 務
Faculty of Pharmaceutical Sciences, Osaka University
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春山 宗忠
Faculty of Pharmaceutical Sciences, Osaka University
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中島 博志
Faculty of Pharmaceutical Sciences, Osaka University
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杢 炳〓
Faculty of Pharmaceutical Sciences, Osaka University
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甲田 伊佐男
Japan and Central Research Laboratories, Green Cross Corporation, Ltd.,
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岩井 正和
Japan and Central Research Laboratories, Green Cross Corporation, Ltd.,
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KOHDA Isao
Japan and Central Research Laboratories, Green Cross Corporation, Ltd.,
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中島 博志
Faculty Of Pharmaceutical Sciences Osaka University
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三村 務
大阪大学薬学部
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Tanaka K
Department Of Molecular Engineering Graduate School Of Engineering Kyoto University
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小浜 靖弘
大阪大学薬学部
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甲田 伊佐男
Central Research Laboratories The Green Cross Corporation
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岩井 正和
Central Research Laboratories The Green Cross Corporation
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Tanaka Ken-ichiro
Faculty Of Pharmaceutical Sciences Okayama University
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杢 炳〓
Faculty Of Pharmaceutical Sciences Osaka University
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春山 宗忠
Faculty Of Pharmaceutical Sciences Osaka University
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甲田 伊佐男
Green Cross Corp. Osaka Jpn
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辻川 和丈
Faculty of Pharmaceutical Sciences, Okayama University
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