A Facile Synthesis of 2-Deoxy-2,3-didehydroneuraminic Acid Derivatives
スポンサーリンク
概要
- 論文の詳細を見る
The 2-thio- or 2-selenoglycosides of N-acetylneuraminic acid methyl ester were transformed by successive treatment with dimethyl(methylthio)sulfonium triflate (DMTST) and 1,8-diazabicyclo[5.4.0]-7-undecene (DBU) to give the correponding methyl 2-deoxy-2,3-didehydroneuraminates in excellent yields. Their acids and thier analogues are sialidase inhibitors of pharmaceutical interest.
- 公益社団法人日本薬学会の論文
- 2000-01-01
著者
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池田 潔
School Of Pharmaceutical Sciences University Of Shizuoka
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Konishi K
School Of Pharmaceutical Sciences University Of Shizuoka
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Tanaka K
Department Of Molecular Engineering Graduate School Of Engineering Kyoto University
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池田 潔
Tanabe Seiyaku Co. Ltd. Saitama Jpn
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Sano K
Meiji Pharmaceutical Univ. Tokyo Jpn
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Tanaka Ken-ichiro
Faculty Of Pharmaceutical Sciences Okayama University
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TANAKA Kiyoshi
School of Pharmaceutical Sciences, University of Shizuoka
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IKEDA Kiyoshi
School of Pharmaceutical Sciences, University of Shizuoka
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KONISHI Koji
School of Pharmaceutical Sciences, University of Shizuoka
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SANO Kimihiko
School of Pharmaceutical Sciences, University of Shizuoka
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Tanaka Katsuyuki
Dept. Biol. Sci. Fac. Sci. Hiroshima Univ.
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Ikeda Kiyoshi
Department Of Biochemistry Osaka University Of Pharmaceutical Sciences
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Tanaka K
Dept. Biol. Sci. Fac. Sci. Hiroshima Univ.
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池田 かおり
Developmental Research Laboratories Shionogi & Co. Ltd.
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Ikeda Kaori
Developmental Research Laboratories Shionogi & Co. Ltd.
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Tanaka Kiyoshi
School Of Pharmaceutical Sciences University Of Shizuoka
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Konishi K
Nippon Dental Univ. Tokyo Jpn
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Ikeda Kiyoshi
School Of Information Science Japan Advanced Institute Of Science And
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