Studies on Pharmacological Activation of Human Serum Immunoglobulin G(IgG) by Chemical Modification and Active Subfragments. VII. Effect of Carboxamidemethylated Fc(CM-Fc) Fragment from Human Serum IgG on Lymphocytes and Macrophages(Pharmacological,Chemic
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概要
- 論文の詳細を見る
The mechanism of the anti-allergic activity of carboxamidemethylated Fc (CM-Fe) was examined in vitro. CM-Fe had no effect on the proliferation of lymphocytes induced by concanavalin A (Con A), lipopolysaccharide (LPS), T cell-dependent mitogen or T cell-independent mitogen. CM-Fc inhibited the activation of glycogen-stimulated guinea pig macrophages by FMLP and A23187, but not by phorbol 12-myristate 13-acetate (PMA).
- 公益社団法人日本薬学会の論文
- 1987-12-25
著者
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横山 和正
Central Research Laboratory, Green Cross Corporation
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伊東 進
阪大・薬
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小浜 靖弘
Faculty of Pharmaceutical Sciences, Osaka University
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大村 孝男
ミドリ十字、中研
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横山 和正
ミドリ十字、中研
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辻川 和丈
阪大薬
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辻川 和丈
Faculty of Pharmaceutical Sciences, Osaka University
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三村 務
Faculty of Pharmaceutical Sciences, Osaka University
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伊東 進
Faculty of Pharmaceutical Sciences, Osaka University
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岡部 勝
Faculty of Pharmaceutical Sciences, Osaka University
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岩井 正和
Central Reserach Laboratories, The Green Cross Corporation
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中島 博志
Faculty of Pharmaceutical Sciences, Osaka University
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中島 博志
Faculty Of Pharmaceutical Sciences Osaka University
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大村 孝男
ミドリ十字中央研究所
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大村 孝男
ミドリ十字・中研
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三村 務
大阪大学薬学部
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岡部 勝
大阪大薬学部
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Tanaka K
Department Of Molecular Engineering Graduate School Of Engineering Kyoto University
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小浜 靖弘
大阪大学薬学部
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岩井 正和
Central Research Laboratories The Green Cross Corporation
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Tanaka Ken-ichiro
Faculty Of Pharmaceutical Sciences Okayama University
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大村 孝男
Central Research Laboratories, The Green Cross Corporation, Ltd.
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Itoh S
Division Of Bio-medical And Immunological Chemistry Faculty Of Pharmaceutical Sciences Osada Univers
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Itoh S
Showa Denko Co. Tokyo Jpn
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岡部 勝
大阪大学 薬
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横山 和正
Central Research Laboratories The Green Cross Corporation
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辻川 和丈
Faculty of Pharmaceutical Sciences, Okayama University
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