Synthesis of Cancer Peptide Antigen-Lipid A Analog Conjugates for Synthetic Vaccines

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概要

• 論文の詳細を見る

• Conjugates 6 and 7 of cancer peptide antigen with N-tetradecanoly L-serine-β-alanine-containing D-glucosamine derivative structurally related to lipid A as an immunoadjuvant were synthesized for the development of totally synthetic vaccines against cancers. The mitogenic activities of compounds 6 and 7 were stronger than that of lipid A analog 3.

• 公益社団法人日本薬学会の論文
• 1999-04-15

著者

• 阿知波 一雄

  静岡県立大学薬学部

• 阿知波 一雄

  School of Pharmaceutical Sciences, University of Shizuoka

• 阿知波 一雄

  静岡県大薬

• 阿知波 一雄

  東大・薬

• 池田 潔

  School Of Pharmaceutical Sciences University Of Shizuoka

• 池田 潔

  Tanabe Seiyaku Co. Ltd. Saitama Jpn

• ACHIWA Kazuo

  School of Pharmaceutical Sciences, University of Shizuoka

• IKEDA Kiyoshi

  School of Pharmaceutical Sciences, University of Shizuoka

• MIYAJIMA Keisuke

  School of Pharmaceutical Sciences, University of Shizuoka

• MARUYAMA Yasufumi

  School of Pharmaceutical Sciences, University of Shizuoka

• Achiwa Kazuo

  School Of Pharmaceutical Sciences University Of Shizuoka

• Achiwa Kazuo

  School Of Pharmaceutical Sciences(laboratory Of Medicinal Chemistry)

• Ikeda Kiyoshi

  Department Of Biochemistry Osaka University Of Pharmaceutical Sciences

• 池田 かおり

  Developmental Research Laboratories Shionogi & Co. Ltd.

• Ikeda Kaori

  Developmental Research Laboratories Shionogi & Co. Ltd.

• Maruyama Yasufumi

  School Of Pharmaceutical Sciences University Of Shizuoka

• Miyajima K

  Department Of Otolaryngology Tokyo Women's Medical University Daini Hospital

• Ikeda Kiyoshi

  School Of Information Science Japan Advanced Institute Of Science And

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