EFFICIENT ASYMMETRIC HYDROGENATION OF IMINES CATALYZED BY A NEUTRAL IRIDIUM(I) COMPLEX OF (4R, 5R)-MOD-DIOP
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概要
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A neutral iridium(I) complex of (4R, 5R)-MOD-DIOP (1b) was found to be an efficient catalyst for the asymmetric hydrogenation of imines, N-(α-methylbenzylidene)benzylamine (4) and 2,3,3-trimethylindolenine (6), in the presence of tetrabutylammonium iodide. A high enantioselectivity with up to 81.4% ee was achieved.
- 公益社団法人日本薬学会の論文
- 1994-09-15
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