Synthesis of Peptides Mimicking Chemokine Receptor CCR5 and Their Inhibitory Effects against HIV-1 Infection

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概要

• 論文の詳細を見る

• Peptides mimicking chemokne receptor CCR5 were synthesized and their anti-HIV-1 activities evaluated. Prepared compounds, especially a sulfated derivatievs, showed significant anti-HIV-1 activities. Furthermore, a hybrid molecule linked to an N-carbomethoxycarbonyl-prolyl-phenylalanine (CPF) moiety had a greater effect.

• 公益社団法人日本薬学会の論文
• 2000-02-01

著者

• 阿知波 一雄

  静岡県立大学薬学部

• 阿知波 一雄

  School of Pharmaceutical Sciences, University of Shizuoka

• 阿知波 一雄

  静岡県大薬

• 阿知波 一雄

  東大・薬

• 池田 潔

  School Of Pharmaceutical Sciences University Of Shizuoka

• Konishi K

  School Of Pharmaceutical Sciences University Of Shizuoka

• Tanaka K

  Department Of Molecular Engineering Graduate School Of Engineering Kyoto University

• 池田 潔

  Tanabe Seiyaku Co. Ltd. Saitama Jpn

• HOSHINO Hiroo

  Department of Hygiene and Virology, Gunma University School of Medicine

• Tanaka Ken-ichiro

  Faculty Of Pharmaceutical Sciences Okayama University

• TANAKA Kiyoshi

  School of Pharmaceutical Sciences, University of Shizuoka

• Hoshino Hiroo

  Department Of Hygiene And Virology Gunma University School Of Medicine

• ACHIWA Kazuo

  School of Pharmaceutical Sciences, University of Shizuoka

• IKEDA Kiyoshi

  School of Pharmaceutical Sciences, University of Shizuoka

• KONISHI Koji

  School of Pharmaceutical Sciences, University of Shizuoka

• Tanaka Katsuyuki

  Dept. Biol. Sci. Fac. Sci. Hiroshima Univ.

• Achiwa Kazuo

  School Of Pharmaceutical Sciences University Of Shizuoka

• Achiwa Kazuo

  School Of Pharmaceutical Sciences(laboratory Of Medicinal Chemistry)

• Ikeda Kiyoshi

  Department Of Biochemistry Osaka University Of Pharmaceutical Sciences

• Tanaka K

  Dept. Biol. Sci. Fac. Sci. Hiroshima Univ.

• Hoshino H

  Department Of Hygiene And Virology Gunma University School Of Medicine

• 池田 かおり

  Developmental Research Laboratories Shionogi & Co. Ltd.

• Ikeda Kaori

  Developmental Research Laboratories Shionogi & Co. Ltd.

• Tanaka Kiyoshi

  School Of Pharmaceutical Sciences University Of Shizuoka

• Konishi K

  Nippon Dental Univ. Tokyo Jpn

• Ikeda Kiyoshi

  School Of Information Science Japan Advanced Institute Of Science And

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