EFFECTS OF THE DIARYLPHOSPHINO GROUPS OF MODIFIED DIOPS ON THE ENANTIOSELECTIVITY AND THE CATALYTIC ACTIVITY OF THEIR PHODIUM(I) COMPLEXES IN THE CATALYTIC ASYMMETRIC HYDROGENATIONS OF ENAMIDES

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概要

• 論文の詳細を見る

• Remarkable effects of the substituted diphenylphosphino groups of modified DIOPs on the enantioselectivity and the catalytic activity were observed in the asymmetric hydrogenation of an electron-rich olefin such as enamide using their rhodium(I) complexes as the catalyst. The cationic rhodium(I) complexes of modified DIOPs bearing electron-donating groups showed higher catalytic activities than that of original DIOP, and the cationic complexes showed better enantioselectivities than the corresponding neutral ones. The cationic rhodium(I) complex of p-methoxy-substituted DIOP was found to be the most efficient catalyst.

• 公益社団法人日本薬学会の論文
• 1992-10-25

著者

• 阿知波 一雄

  School of Pharmaceutical Sciences, University of Shizuoka

• 森本 俊明

  School Of Pharmaceutical Sciences University

• 千葉 三男

  School Of Pharmaceutical Sciences University Of Shizuoka

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