Synthesis of Optically Active Lipopeptide Analogs from the Outer Membrane of Escherichia coli
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概要
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The synthesis of optically active lipopeptide derivatives has been accomplished by the use of chiral glycerol derivatives. Lipopeptide derivatives with (R)-glycerol moieties showed higher mitogenic activities than those with the (S)-configuration. N-2,2,2-Trichloroethoxycarbonyl lipopeptide derivatives increased mitogenic activity.
- 1991-10-25
著者
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竹元 万寿美
School of Pharmaceutical Sciences, University of Shizuoka
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阿知波 一雄
School of Pharmaceutical Sciences, University of Shizuoka
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阿知波 一雄
静岡県大薬
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栗村 宗明
School of Pharmaceutical Sciences, University of Shizuoka
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栗村 宗明
School Of Pharmaceutical Sciences University Of Shizuoka
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竹元 万寿美
静岡県大薬
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Takemoto Masumi
School Of Pharmaceutical Sciences(laboratory Of Medicinal Chemistry)
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