Efficient Asymmetric Hydrogenation of α-Amino Ketone Derivatives. A Highly Enantioselective Synthesis of Phenylephrine, Levamisole, Carnitine and Propranolol
スポンサーリンク
概要
- 論文の詳細を見る
The complexes of pyrrolidine bisphosphine ligands (CPMs) with rhodium (I) were found to be efficient catalysts for asymmetric hydrogenation of α-amino ketone hydrochloride derivatives. Utilizing this methodology, we have developed efficient asymmetric syntheses of the optically active β-amino alcohols, phenylephrine, levamisole, carnitine and propranolol.
- 公益社団法人日本薬学会の論文
- 1995-05-15
著者
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阿知波 一雄
静岡県立大学薬学部
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阿知波 一雄
School of Pharmaceutical Sciences, University of Shizuoka
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阿知波 一雄
静岡県大薬
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桜庭 俊司
School of Pharmaceutical Sciences, University of Shizuoka
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高橋 寿
School Of Pharmaceutical Sciences University Of Shizuoka
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竹田 榮夫
School of Pharmaceutical Sciences, University of Shizuoka
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竹田 榮夫
School Of Pharmaceutical Sciences University Of Shizuoka
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桜庭 俊司
School Of Pharmaceutical Sciences University Of Shizuoka
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Sakuraba Shunji
School Of Pharmaceutical Sciences University Of Shizuoka
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