1,3-Dipolar Cycloaddition of the Simplest N-Acylazomethine Ylide Leading to 3- or 3,4-Substituted N-Acylpyrrolidines
スポンサーリンク
概要
- 論文の詳細を見る
The 1,3-dipolar cycloaddition of intermediary N-acylazomethine ylides, formed from 1,3,5-tris (trimethylsilylmethyl) hexahydro-1,3,5-triazine and acyl halides, to conjugated olefinic dipolarophiles has been found to give 3- or 3,4-substituted N-acylpyrrolidines in good yields.
- 公益社団法人日本薬学会の論文
- 1985-10-25
著者
-
森本 俊明
Shizuoka College of Pharmacy
-
阿知波 一雄
Shizuoka College of Pharmacy
-
森本 俊明
School Of Pharmaceutical Sciences University
-
根津 喜隆
Shizuoka College of Pharmacy
関連論文
- A New Insertion Reaction of Diazoalkanes with Dialkylaminomethyl Esters of Dialkyldithiocarbamic Acid and of Ethylxanthic Acid
- Antitumor Activity and Lethal Toxicity of Chemically Synthesized Tetraacetyl-2-keto-3-deoxyoctonic Acid-(α2→6)-D-glucosamine Analogues of Lipid A(Biological)
- Comparison of Biological Activities of Chemically Synthesized Monosaccharide Analogues of Reducing and Nonreducing Sugar Moieties of Lipid A(Blological)
- MITOGENIC ACTIVITY OF CHEMICALLY SYNTHESIZED TETRAACETYL-2-KETO-3-DEOXYOCTONIC ACID-(α 2→6)-D-GLUCOSAMINE ANALOGUES OF LIPID A
- ANTITUMOR ACTIVITY AND BIOLOGICAL EFFECTS OF CHEMICALLY SYNTHESIZED MONOSACCHARIDE ANALOGUES OF LIPID A IN MICE
- Trifluoromethanesulfonic Acid-Promoted Reaction of Hexahydro-1,3,5-triazines.Introduction of a Secondary Aminomethyl Grouping into Carboxylates at the α-Position through Ketene Silyl Acetals
- Pyrrolidine-Forming 1,3-Dipolar Cycloaddition of N-(Phenylthiomethyl)-α-amino Acid Esters
- Primary Aminomethylation at the α-Position of Carboxylic Acids and Esters. Trimethylsilyl Triflate-Catalyzed Reaction of Ketene Silyl Acetals with N, N-Bis (trimethylsilyl) methoxymethylamine
- 1,3-DIPOLAR CYCLOADDITION LEADING TO N-ALKYLPYRROLIDINES
- 1,3-Dipolar Cycloaddition Leading to N-Acylated Pyrrolidines and 2,5-Dihydropyrroles
- Decarboxylation Reaction. X. Introduction of a Carbon Unit at the α-Position of Amines by Reaction of Hexahydro-1,3,5-triazines with Carboxylic Acids
- トリクロロ酢酸イオンの脱炭酸を含むトリクロロ酢酸およびその無水物の反応
- Synthesis of Deoxyobtusilactone A
- A 1,3-Dipolar Cycloaddition of Alicyclic Methylene Iminium Ylide to form Pyrrolizidine Nuclei and Its Application to Synthesis of Pyrrolizidine Alkaloids
- N-Alkylamidomethylation at Electron-rich Carbons in the 1,3,5-Trialkylhexahydro-1,3,5-triazine-Acetyl Chloride System
- 25 触媒的不斉水素化を鍵反応とする光学活性リグナン類の合成(口頭発表の部)
- TOTAL SYNTHESIS OF PROTEUS MIRABILIS LIPID A(Communication to the Editor)
- Thiocarbonyl Ylides. VI, New Generation of Thiocarbonyl Ylides from Organosilicon Compounds Containing Sulfur and Their 1,3-Cycloadditions(Organic,Chemical)
- Lipid A and Related Compounds. XI. New, Efficient Synthesis of Lipid X(Organic,Chemical)
- EFFICIENT SYNTHESIS OF NOVEL MONOSACCHARIDE ANALOGS OF LIPIDS A
- A NEW METHODOLOGY FOR CHEMOSELECTION OF ONE AMINO AND FOUR HYDROXYL GROUPS OF GLUCOSAMINE DERIVATIVES AND ITS USE FOR SYNTHESIS OF LIPID X
- Enzymes and Catalysts. I. Pig Liver Esterase-Catalyzed Hydrolysis of Heterocyclic Diesters(Organic,Chemical)
- Synthesis of Proline Derivatives by 1,3-Dipolar Cycloaddition of Azomethine Ylide Generated from an Organosilicon Compound(Organic,Chemical)
- Evidence for Ambivalent Azomethine Ylide Intermediate in the 1, 3-Cycloaddition of Trimethylsilylmethylamine Derivatives(Organic,Chemical)
- Trifluoroacetic Acid-Catalyzed 1,3-Cycloaddition of the Simplest Iminium Ylide Leading to 3-or 3,4-Substituted Pyrrolidines and 2,5-Dihydropyrroles
- A DEFINITE EVIDENCE ON THE AMBIVALENT AZOMETHINE YLIDE INTERMEDIATE IN TRIFLUOROACETIC ACID- AND FLUORIDE ANION-PROMOTED 1,3-CYCLO-ADDITIONS INVOLVING THE SILICON-CARBON BOND CLEAVAGE
- SYNTHESIS OF ATROPISOMERIC BIPHENYLBISPHOSPHINE, 6,6'-BIS(DICYCLO-HEXYLPHOSPHINO)-3,3'-DIMETHOXY-2,2', 4,4'-TETRAMETHYL-1,1'-BIPHENYL AND ITS USE IN RHODIUM(I)-CATALYZED ASYMMETRIC HYDROGENATION
- SYNTHESIS OF AXIALLY DISSYMMETRIC BIPHENYLBISPHOSPHINE LIGANDS, BIMOPS AND ASYMMETRIC HYDROGENATIONS OF β-KETO ESTER AND α, β-UNSATURATED CARBOXYLIC ACID CATALYZED BY THEIR RUTHENIUM (II) COMPLEXES
- A Novel 2,3-Pyrrolidinedione Ring Closure of 1,1,1,5,5,5-Hexachloro-4-dimethylamino-3,3-dimethyl-2-pentanone
- Reaction of N, N-Dialkylaminomethyl Arenesulfonates with Diazoalkanes
- Decarboxylation Reactions. IX. Reaction of Enamines with Trichloroacetic Anhydride
- Decarboxylation Reactions. VI. Reaction of α-Arylmethyleneamino-substituted Derivatives of Pyridine, Quinoline, and Isoquinoline with Trichloroacetic Anhydride
- Reactions of α-Alkyl- and α-Aryl-substituted N-Benzylideneamines with Trihaloacetylating Agents
- Reaction of Schiff Bases with Trichloroacetyl Chloride in the Presence of Triphenylphosphine
- Decarboxylation Reactions. IV. Reaction of Schiff Bases with Trichloroacetic Anhydride
- Reaction of 1-Pyrrolidino-1-cyclohexene with Imidoyl Chlorides and a Route to Producing Phenanthridines
- Intramolecular Aldol Condensations of the Reaction Products formed from 2,4-Pentanedione and Aldehydes
- Synthesis of (β-N-Sulfonylaminoalkyl)phosphines and Their Use in Palladium-Mediated Asymmetric Synthesis
- EFFICIENT ASYMMETRIC HYDROGENATION OF IMINES CATALYZED BY A NEUTRAL IRIDIUM(I) COMPLEX OF (4R, 5R)-MOD-DIOP
- Preparations of Chiral Pyrrolidinebisphosphines Bearing Two Different Types of Phosphino Groups and Their Use in Efficient Catalytic Asymmetric Hydrogenation
- Highly Regioselective Synthesis of Trisubstituted Pyrrolidines by 1,3-Cydoaddition(Organic,Chemical)
- One-Pot Synthesis of N-Alkylpyrrolidines by 1,3-Dipolar Cycloaddition(Organic,Chemical)
- Trimethylsilyl Triflate-Catalyzed 1,3-Dipolar Cycloaddition Leading to N-Unsubstituted Pyrrolidines
- Synthesis of Efficient Chiral Bisphosphine Ligands, Modified DIOPs, (4R, 5R)-4-(Diaryl- or dialkylphosphino)methyl-5-(diarylphosphino)methyl-2,2-dimethyl-1,3-dioxolanes, and Their Use in Rhodium(I)-Catalyzed Asymmetric Hydrogenations
- EFFECTS OF THE DIARYLPHOSPHINO GROUPS OF MODIFIED DIOPS ON THE ENANTIOSELECTIVITY AND THE CATALYTIC ACTIVITY OF THEIR PHODIUM(I) COMPLEXES IN THE CATALYTIC ASYMMETRIC HYDROGENATIONS OF ENAMIDES
- EFFICIENT SYNTHESIS OF NATURAL (+)-COLLINUSIN USING CATALYTIC ASYMMETRIC HYDROGENATION WITH A CHIRAL BISPHOSPHINE-RHODIUM(I) COMPLEX
- トリクロロ酢酸イオンの脱酸素を含むトリクロロ酢酸およびその無水物の反応
- 超効率不斉水素化触媒の開発と実用的不斉合成への応用
- 1,3-Dipolar Cycloaddition of the Simplest N-Acylazomethine Ylide Leading to 3- or 3,4-Substituted N-Acylpyrrolidines
- SYNTHESIS OF BIOLOGICALLY ACTIVE TETRAACETYL-3-DEOXY-D-MANNO-2-OCTULOSONIC ACID(KDO)-(α2→6)-D-GLUCOSAMINE ANALOGS OF LIPID A