Cularine and Related Compounds. V. Investigation of the Ullmann Reaction Products of Methyl (2-Bromo-4,5-dimethoxyphenyl) acetate with Phenolic Compounds, and an Approach to the Total Synthesis of Cularine.
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概要
- 論文の詳細を見る
Preparation of the cyclic amide (II) as the key intermediate for the synthesis of cularine was elaborated. Bischler-Napieralski cyclization of this amide appeared to proceed as expected to give the desired isoquinoline derivative, didehydronorcularine, in a crude state, which, however, was readily oxidized and turned during purification into the corresponding ketone derivative, which was characterized as its picrate.
- 公益社団法人日本薬学会の論文
- 1963-10-25
著者
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福本 圭一郎
東北大・薬
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亀谷 哲治
Pharmaceutical Institute Medical Faculty University Of Osaka
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中野 卓雄
Pharmaceutical Institute, Tohoku University
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福本 圭一郎
Pharmaceutical Institute Tohoku University School Of Medicine
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渋谷 皓
Pharmaceutical Institute, Tohoku University School of Medicine
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渋谷 皓
東北大学薬学部
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中野 卓雄
Pharmaceutical Institute Tohoku University
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