Studies on the Syntheses of Tetracycline Derivatives. III. Synthetic Approach to Adriamycin-Synthesis of the Linear Tetracyclic Skeleton having the Same BC Ring System with Adriamycin

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概要

• 論文の詳細を見る

• Cycloaddition of 1-acetoxybenzocyclobutene (21) with naphthoquinone (8) gave naphthacene-5,12-quinone (22) which was converted into 6,11-dihydroxynaphthacene-5,12-quinone (25) by three steps. Synthetic trial of 6-oxygenated naphthacene-5,12-quinones from naphthacene-5,12-quinones are also described.

• 社団法人日本薬学会の論文
• 1978-12-25

著者

• 竹下 光弘

  Pharmaceutical Institute Tohoku University

• 亀谷 哲治

  Pharmaceutical Institute, Tohoku University School of Medicine

• 高野 誠一

  Pharmaceutical Institute Tohoku University

• 福本 圭一郎

  東北大・薬

• 福本 圭一郎

  Pharmaceutical Institute, Tohoku University

• 千尋 正利

  Pharmaceutical Institute, Tohoku University

• 高橋 喜美男

  Pharmaceutical Institute, Tohoku University

• 千尋 正利

  東北大薬

• 千尋 正利

  Tokushima Research Institute, Otsuka Pharmaceutical Co., Ltd.,

• 亀谷 哲治

  Pharmaceutical Institute Medical Faculty University Of Osaka

• 福本 圭一郎

  Pharmaceutical Institute Tohoku University School Of Medicine

• 千壽 正利

  Tokushima Research Institute Otsuka Pharmaceutical Co. Ltd.

• 千尋 正利

  Tokushima Research Institute Otsuka Pharmaceutical Co. Ltd.

• 高橋 喜美男

  Pharmaceutical Institute Tohoku University

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