An Abnormal Formation of Indane from N-Phenethylphenylpropionamide under Bischler-Napieralski Reaction Conditions

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概要

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• A treatment of N-(3-acetoxy-4-benzyloxyphenethyl)-4-benzyloxy-3-methoxyphenylpropionamide (17) with phosphoryl chloride gave 1-(3-acetoxy-4-benzyloxyphenethyl)-imino-6-benzyloxy-5-methoxyindane (21) instead of the normal product, 3,4-dihydroisoquinoline (20). The structure of 21 was determined by chemical method and by an alternative synthesis of the indane derivative (25) derived from 21.

• 公益社団法人日本薬学会の論文
• 1977-05-25

著者

• 亀谷 哲治

  Pharmaceutical Institute, Tohoku University School of Medicine

• 福本 圭一郎

  東北大・薬

• 福本 圭一郎

  Pharmaceutical Institute, Tohoku University

• 亀谷 哲治

  Pharmaceutical Institute Medical Faculty University Of Osaka

• 福本 圭一郎

  Pharmaceutical Institute Tohoku University School Of Medicine

• 佐藤 嘉生

  Pharmaceutical Institute Tohoku University

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