Bisbenzylisoquinoline Alkaloids and Related Compounds. IX. A Modified Total Synthesis of Stereoisomeric Mixture of Magnolamine : Studies on the Syntheses of Heterocyclic Compounds. CXLV.
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概要
- 論文の詳細を見る
O-Benzylmagnolamine (XXI) was successfully obtained by the modified Ullmann reaction of dl-7-benzyloxy-1-(4,5-bisbenzyloxy-2-bromobenzyl)-1,2,3,4-tetrahydro-6-methoxy-2-methylisoquinoline (III) with 7-benzyloxy-1-(4-hydroxybenzyl)-1,2,3,4-tetrahydro-6-methoxy-2-methylisoquinoline (IV) without any detectable side reaction in thin-layer chromatography. Since removal of benzyl group by hydrolysis had already afforded magnolamine (I), a modified total synthesis of stereoisomeric mixture of magnolamine has been accomplished.
- 社団法人日本薬学会の論文
- 1966-09-25
著者
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八木 治彦
Pharmaceutical Institute Tohoku University
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亀谷 哲治
Pharmaceutical Institute, Tohoku University School of Medicine
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亀谷 哲治
Pharmaceutical Institute Medical Faculty University Of Osaka
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金田 重夫
東北大学医学部薬学科
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金田 重夫
Pharmaceutical Institute, Tohoku University School of Medicine
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